Amprilan NL Tablets 2.5mg/12.5mg: Comprehensive Guide to This Antihypertensive Medication

Amprilan NL tablets 2.5mg/12.5mg are a fixed-dose combination medication used for the treatment of high blood pressure (hypertension). This comprehensive guide provides detailed information about Amprilan NL, including its uses, dosage, side effects, interactions, precautions, and more.

Understanding Amprilan NL

Amprilan NL combines two active ingredients:

• Ramipril: An ACE (angiotensin-converting enzyme) inhibitor that helps relax blood vessels and lower blood pressure.
• Hydrochlorothiazide: A thiazide diuretic that helps remove excess fluid and salt from the body, thus lowering blood pressure.

Key Benefits of Amprilan NL

• Effective blood pressure control: Amprilan NL provides a powerful, dual-action approach to managing hypertension.
• Convenient once-daily dosage: Simplifies treatment adherence.
• Proven efficacy: Extensive research supports the effectiveness of Amprilan NL in reducing blood pressure.

Uses of Amprilan NL

Amprilan NL is indicated for the treatment of:

• Arterial hypertension: High blood pressure.
• Chronic heart failure: As part of combination therapy.
• Diabetic nephropathy: Kidney damage related to diabetes.
• Nephropathy: Kidney damage from other chronic kidney diseases.
• Reducing cardiovascular risk: In patients with a high risk of heart attack, stroke, or cardiovascular mortality.

Important Precautions and Contraindications

Amprilan NL is not suitable for everyone. It’s crucial to discuss your medical history with your doctor before taking this medication.

Contraindications:

• Hypersensitivity to ramipril, hydrochlorothiazide, or other ACE inhibitors.
• Angioedema in the past.
• Significant bilateral renal artery stenosis.
• Stenosis of a single kidney artery.
• Recent kidney transplant.
• Hemodialysis.
• Severe renal failure.
• Significant aortic or mitral stenosis.
• Hypertrophic obstructive cardiomyopathy (HOCM).
• Chronic heart failure in the decompensated stage.
• Severe hypotension.
• Primary hyperaldosteronism.
• Galactose intolerance, lactase deficiency, or glucose-galactose malabsorption syndrome.
• Nephropathy treated with corticosteroids, NSAIDs, immunomodulators, or cytostatics.
• Pregnancy and lactation.

Precautions:

• Severe coronary or cerebral artery disease.
• Malignant hypertension.
• Unstable angina pectoris.
• Severe ventricular arrhythmias.
• Chronic heart failure (Class IV NYHA).
• Decompensated cor pulmonale.
• Renal or liver failure.
• Hyperkalemia.
• Hyponatremia.
• Conditions accompanied by a decrease in blood volume.
• Systemic connective tissue diseases.
• Diabetes.
• Bone marrow suppression.
• Elderly age.
• Hemodialysis using high-flow polyacrylonitrile membranes.
• Before LDL apheresis procedure.
• Simultaneous desensitizing therapy with allergens.

Dosage and Administration

Amprilan NL tablets should be swallowed whole with plenty of water, regardless of meals. The dosage is determined by your doctor based on your individual needs and response to the medication.

Possible Side Effects

Like all medications, Amprilan NL can cause side effects. Some common side effects include:

• Dizziness
• Headache
• Dry cough
• Fatigue
• Nausea
• Diarrhea

Serious side effects are rare but may include:

• Angioedema
• Severe hypotension
• Hyperkalemia
• Liver damage
• Renal failure

Drug Interactions

Amprilan NL can interact with other medications. It’s crucial to inform your doctor about all the medications you’re currently taking, including over-the-counter drugs, herbal supplements, and vitamins.

Driving and Operating Machinery

Amprilan NL may cause dizziness, so caution is advised when driving or operating machinery.

Pregnancy and Lactation

Amprilan NL is contraindicated in pregnancy. Breastfeeding should be discontinued if you need to take Amprilan NL.

Overdose

If you suspect an overdose of Amprilan NL, seek immediate medical attention.

Amprilan NL is a powerful medication that can effectively manage high blood pressure. However, it’s crucial to use it as prescribed by your doctor. This guide provides general information, and it’s not a substitute for professional medical advice. Always consult your doctor for personalized guidance and treatment plans.