Valerian Forte tablets №10х3

Name:
Valerian Forte tabl. Producer: Borisov ZMP INN: Valerian rhizomes with roots FTG: Sedative of plant origin
Description:
: Gray tablets with dark patches, round with a biconvex surface. Composition One tablet contains: active substance – thick valerian extract – 150 mg (from rhizomes with valerian roots (2.4-2.7): 1, extractant – ethyl alcohol 40% (v / v)); excipients: basic magnesium carbonate, potato starch, talc, gelatin, sodium croscarmellose. Pharmacotherapeutic group Other hypnotics and sedatives. ATX code: N05CM09. Pharmacological properties Pharmacodynamics Preparations of valerian root have a sedative effect, promote the onset of sleep. These effects cannot be explained by the action of any one component of valerian. Some of the mechanisms of action that cause these clinical effects have been identified for various components of valerian root (sesquiterpenoids, lignans, flavonoids) and include effects on the GABA system, A1 adenosine receptors and 5-HT1A receptors. The sedative effect when using valerian root preparations manifests itself slowly, but quite stably and fully develops only with a systematic course of treatment. Pharmacokinetics The pharmacokinetics of valerian has not been studied enough, which is due to the impossibility of accurately identifying the active principle of the drug. Indications for use Used in the complex therapy of functional disorders of the nervous system (neurasthenia) and sleep disorders. Use for the indicated purposes is based on long-term experience only. Dosage and administration Adults and children over 12 years of age are prescribed orally 300-600 mg (2-4 tablets) 1-3 times a day after meals. With increased nervous excitability, it is recommended to take up to 3 times a day. In case of sleep disorders, it is recommended to take half an hour to one hour before bedtime, and, if necessary, an additional dose of the drug beforehand in the evening. In cases of urgent need to reduce the symptoms of mental arousal and sleep disorders, the use of valerian preparations is not recommended due to the gradual development of the effect. The recommended duration of treatment is 2-4 weeks. Features of use in patients with impaired liver and / or kidney function: no information available. Side effects Possible development of allergic reactions (skin rash, itching, flushing, swelling of the skin), headache, general weakness, drowsiness, irritability, anxiety, gastrointestinal disorders (nausea, abdominal pain), decreased performance. Large doses can lead to bradycardia and arrhythmia, as well as decreased intestinal motility (constipation). In case of adverse reactions, including those not listed in the instructions for use, you should consult a doctor. Contraindications Hypersensitivity to valerian, as well as excipients that make up the drug, pregnancy, lactation, children under 12 years of age. Interaction with other medicinal products Data on interactions with other medicinal products are limited. Clinically significant interactions with drugs metabolized by CYP2D6, CYP3A4 / 5, CYP1A2 or CYP2E1 enzymes have not been observed. The combination of valerian preparations with synthetic sedatives requires prior consultation with a doctor and supervision of a doctor during treatment. Precautions Due to the gradual development of the effect, valerian preparations are not recommended for use in cases of urgent need to reduce the symptoms of mental arousal and sleep disturbances. It is necessary to inform the patient to consult a doctor if, within two weeks of continuous use of the drug, the symptoms of the disease persist or worsen. Use in children The safety of use in children under 12 years of age has not been established. Due to the lack of sufficient data, it is not recommended to prescribe to children under 12 years of age. Pregnancy and lactation The safety of use during pregnancy and lactation has not been established. Due to the lack of sufficient data, it is not recommended to use during pregnancy and lactation. Influence on the ability to drive vehicles and control mechanisms During treatment, you should refrain from driving vehicles and working with moving mechanisms. Overdose Long-term use of the drug in doses exceeding the recommended ones causes a feeling of depression, headache, drowsiness, decreased performance, discomfort from the gastrointestinal tract, nausea, and impaired cardiac activity (bradycardia). With a single dose of an excessively high dose (about 20 g of valerian root), it is possible to develop spastic abdominal pain, chest tightness, dizziness, general weakness, hand tremors and dilated pupils. In case of overdose, you should consult a doctor. With a single dose of a high dose, it is recommended to induce vomiting, gastric lavage (no later than two hours after taking the drug). With prolonged use of the drug in high doses, drug withdrawal is recommended. There is no specific antidote. Symptomatic therapy. Upakovka10 tablets in a blister pack of PVC film and aluminum foil. 3 or 6 blister packs, together with the leaflet, are placed in a pack of cardboard (No. 10×3, No. 10×6). Storage conditions In a place protected from light and moisture, at a temperature not exceeding 25 ° C. Keep out of the reach of children. Shelf life 2 years. Do not use the drug after the expiration date. Terms of dispensing from pharmaciesWithout a prescription. Buy Valerian Forte tablets No. 10×3 Price for Valerian Forte tablets No. 10×3 Instructions for use for Valerian Forte tablets No. 10×3