Sulfargin ointment 10mg/g 50g №1

Name:
Sulfargin ointment for nar.prim.10mg/g in tubes 50g in pack No. 1
Description:
Ointment for external use of white or almost white color, with a characteristic odor. The main active ingredient Silver sulfadiazine Release form Ointment for external use of white or almost white color, with a characteristic odor. 1 g silver sulfadiazine 10 mg Excipients: vaseline oil – 230 mg, propylene glycol – 100 mg, cetostearyl alcohol – 60 mg, glyceryl monostearate 40-55 – 30 mg, polysorbate 80 – 20 mg, methyl parahydroxybenzoate – 0.8 mg, propyl parahydroxybenzoate – 0.2 mg , purified water – up to 1 g. 50 g – aluminum tubes (1) – packs of cardboard. Dosage 10 mg / g in tubes 50 g in pack No. 1 Special instructions When applying the ointment on a large surface, the functional state of the kidneys, liver and the content of blood cells should be monitored; prescribe to patients a plentiful alkaline drink. Pharmacological action Broad-spectrum antimicrobial agent, sulfanilamide. It has a bactericidal effect. The drug is active against gram-positive and gram-negative bacteria (Escherichia coli, Proteus spp., Staphylococcus spp., Klebsiella spp.), as well as Candida spp. and dermatophytes. The bactericidal properties of Sulfargin ointment are due to the activity of silver ions, which are released in the wound as a result of the dissociation of the silver salt of sulfadiazine; the release of silver ions occurs gradually (moderate dissociation), ensuring the constancy of the antimicrobial action. The bactericidal activity of silver ions is complemented by the bacteriostatic effect of sulfadiazine (also released during the dissociation of the silver salt of sulfadiazine). Sulfargin is characterized by moderate osmotic activity and does not have necrolytic properties. When applied externally, the ointment can be absorbed from a damaged burn or wound surface up to 1% of silver ions and up to 10% of sulfadiazine from the total amount of sulfadiazine silver salt applied to the wound. Pharmacokinetics Data on the pharmacokinetics of Sulfargin are not available. Indications for use In adults and children over 1 year old for the prevention and treatment of purulent wounds and burns with mild exudation, as well as trophic ulcers, bedsores: – when treating fresh burn surfaces to prevent the development of infection; – for the treatment of wound and burn surfaces in the first stage of the wound process with mild exudation; – for the treatment of wounds and burns of I-IIIA degree in the second and third stages of the wound process; – for the treatment of trophic ulcers, bedsores, long-term non-healing wounds (including stump wounds). Dosage and administration Apply externally. After surgical treatment of the wound and removal of necrotic tissues, the ointment is applied to the damaged surface with a thin layer (2-4 mm) under a bandage or in an open way. The dressing is changed 1-2 times / day or less. The maximum single dose is 300 g. The duration of treatment is up to 3 weeks. Use during pregnancy and lactation The drug is contraindicated during pregnancy and lactation. Precautions When applying the ointment on a large surface, the functional state of the liver should be monitored. When applying the ointment on a large surface, the functional state of the kidneys should be monitored. The drug is contraindicated in children under 1 year of age. Interaction with other drugs Data on the drug interaction of the drug Sulfargin is not provided. Contraindications – pregnancy; – lactation period; – severe deficiency of glucose-6-phosphate dehydrogenase; – children’s age up to 1 year; – Hypersensitivity to sulfonamides. Sulfargin should not be used to treat deep purulent wounds and burn surfaces with abundant exudation. Composition In 1 g silver sulfadiazine 10 mg Excipients: vaseline oil – 230 mg, propylene glycol – 100 mg, cetostearyl alcohol – 60 mg, glyceryl monostearate 40-55 – 30 mg, polysorbate 80 – 20 mg, methyl parahydroxybenzoate – 0.8 mg, propyl parahydroxybenzoate – 0.2 mg, purified water – up to 1 g. Overdose Data on the overdose of the drug Sulfargin are not provided. Side effects Systemic reactions: with prolonged use of Sulfargin on extensive burn surfaces, digestive disorders and changes in the picture of peripheral blood (leukopenia), dyspeptic symptoms and skin manifestations of allergic reactions characteristic of sulfanilamide preparations are possible. Local reactions: rarely – a short-term local irritant effect (burning, pain), which usually disappear on their own 5-10 minutes after applying a bandage with ointment. Storage conditions Ointment in tubes should be stored at a temperature not exceeding 25 ° C. Buy Sulfargin ointment 10mg/g 50g №1 Price for Sulfargin ointment 10mg/g 50g №1