Spazmaton solution for intramuscular injection in ampoules 5ml №10

NameSpazmaton rr di in amp 5 ml in pack No. 10 Main active ingredient Metamizole sodium + pitofenone + fenpiverinium bromide Form of release solution for injection Dosage 5 ml Indications for use Pain syndrome (mild or moderately pronounced) with spasms of smooth muscles of internal organs: renal colic, Bladder; biliary colic, intestinal colic; algomenorrhea. For short-term treatment: arthralgia, myalgia, neuralgia, sciatica. As an auxiliary drug: pain syndrome after surgical interventions and diagnostic procedures. Dosage and administration The drug is administered intravenously (in / in) and intramuscularly (in / m). Adults and adolescents over 15 years of age with acute severe colic are injected intravenously slowly (1 ml over 1 minute), 2 ml; if necessary, re-introduce after 6 to 8 hours. V / m – 2 to 5 ml of solution 2 to 3 times a day. The daily dose should not exceed 10 ml. Duration of treatment – no more than 5 days. Children in / in and / m are prescribed depending on age in the following doses: 3 – 5 months (5 – 8 kg): only in / m, the recommended single dose is 0.1 ml, the maximum daily dose is 0.8 ml (0 .2 ml 4 times / day); 6 – 11 months (8 – 10 kg) – only in / m – the recommended single dose is 0.1 ml, the maximum daily dose is 1.2 ml (0.3 ml 4 times / day); 1 – 2 years (12 – 14 kg) – the recommended single dose is 0.2 ml, the maximum daily dose is 1.6 ml (0.4 ml 4 times / day); 3 – 4 years (14 – 18 kg) – the recommended single dose is 0.2 ml, the maximum daily dose is 2.4 ml (0.6 ml 4 times / day); 5 – 7 years (24 – 30 kg) – the recommended single dose is 0.4 ml, the maximum daily dose is 3.2 ml (0.8 ml 4 times / day); 8 – 11 years old (31 – 45 kg) – the recommended single dose is 0.5 ml, the maximum daily dose is 4 ml (1 ml 4 times / day); 12 – 14 years (body weight about 50 kg) – the recommended single dose is 0.8 ml, the maximum daily dose is 6.4 ml (1.6 ml 4 times / day); Before the introduction of the solution, the ampoule should be warmed in the hand. Use during pregnancy and lactation It is not recommended to use the drug in the first trimester and in the last 6 weeks of pregnancy. In other periods of pregnancy, the appointment is possible only under strict indications, under the supervision of a doctor. During lactation, breastfeeding should be discontinued for the duration of spasmaton treatment. Precautions Renal / liver failure, bronchial asthma, “aspirin” triad, tendency to arterial hypotension, hypersensitivity to other non-steroidal anti-inflammatory drugs, prolonged alcohol abuse. Interaction with other drugs Due to the high likelihood of developing pharmaceutical incompatibility, spasmaton should not be mixed with any other drugs in the same syringe. Enhances the effects of ethanol. Radiopaque drugs, colloidal blood substitutes and b-lactam antibiotics increase the nephrotoxic effect of metamizole sodium. With simultaneous use with other analgesics, antipyretics and non-steroidal anti-inflammatory drugs, mutual enhancement of toxic effects is possible. Phenylbutazone, barbiturates and other inducers of microsomal liver enzymes, when administered simultaneously, reduce the effectiveness of metamizole sodium. The effect is enhanced by codeine, H2-histamine receptor blockers and propranolol (slows down the inactivation of metamizole sodium). Increases the risk of developing leukopenia when used together with thiamazole and cytostatic agents. Increases the effect of oral sugar-lowering agents, indirect anticoagulants, glucocorticosteroids and indomethacin due to their displacement from the connection with blood proteins. With simultaneous use with phenothiazine derivatives, severe hyperthermia may develop. Tricyclic antidepressants, combined oral contraceptives and allopurinol slow down the metabolism of metamizole and increase its toxicity. If you are taking other medicines, you must inform your doctor. Contraindications Hypersensitivity (including to pyrazolone derivatives), suppression of bone marrow hematopoiesis, severe hepatic and / or renal failure, deficiency of glucose-6-phosphate dehydrogenase, tachyarrhythmias, severe angina pectoris, decompensated chronic heart failure, angle-closure glaucoma, benign prostatic hyperplasia (with clinical manifestations), intestinal obstruction, megacolon, collapse, pregnancy (especially in the first trimester and in the last 6 weeks), lactation. For intravenous administration – infancy (up to 3 months) or body weight less than 5 kg. Composition 5 ml of solution contain: active ingredients: metamizole sodium – 2500 mg; pitofenone hydrochloride – 10 mg; fenpiverinium bromide – 0.1 mg; excipients: hydrochloric acid, water for injection. Overdose Symptoms: nausea, vomiting, gastralgia, lowering blood pressure, tachycardia, shortness of breath, tinnitus, weakness, drowsiness, confusion, convulsions, impaired liver and kidney function. Treatment: gastric lavage, saline laxatives, administration of activated charcoal; carrying out forced diuresis, hemodialysis, with the development of a convulsive syndrome – intravenous administration of diazepam and high-speed barbiturates. It is necessary to stop using the drug and consult a doctor. Side effects Allergic reactions: urticaria, rarely: malignant exudative erythema, bronchospasm, anaphylactic shock. From the urinary system: impaired renal function, oliguria, anuria, proteinuria, interstitial nephritis, urine staining red. From the side of the cardiovascular system: lowering blood pressure, tachycardia. On the part of the hematopoietic organs: thrombocytopenia, leukopenia, agranulocytosis (may be manifested by the following symptoms: unmotivated rise in temperature, chills, sore throat, difficulty swallowing, stomatitis, as well as the development of vaginitis or proctitis). Local reactions: with intravenous administration, infiltrates are possible at the injection site. If you experience any other reactions not listed in this package leaflet, you should stop taking the medicine and contact your doctor. Storage conditions In a place protected from light, at a temperature not exceeding 25 ° C. Keep out of the reach of children. Buy Spasmaton solution for intramuscular injection in ampoules 5ml No. 10 Price for Spasmaton solution for intramuscular injection in ampoules 5ml No. 10