Sedavit tablets №10×2

Name:
Sedavit tab. in bl. in pack. No. 10х2
Description:
Tablets from beige to brown color, interspersed, oval, with a biconvex surface, with a risk on one side of the tablet. The main active ingredient Sedavit thick extract Release form 10 tablets in a blister strip package made of a light-protective polyvinyl chloride film of green color and aluminum foil with a lacquered print. 2 blister packs together with instructions for use in a pack of cardboard boxes. Dosage No. 10×2 Pharmacodynamics A complex extract for the drug Sedavit is obtained from rhizomes with valerian roots, hawthorn fruits, St. John’s wort, peppermint leaves, hop cones. The pharmacological action of the drug is due to the properties of the components that make up its composition. Biologically active substances of the extracts have a sedative effect, facilitate the onset of sleep. Vitamins (pyridoxine hydrochloride (vitamin B6) and nicotinamide (vitamin PP)) are involved in the processes of tissue respiration, fat and carbohydrate metabolism. Pharmacokinetics No data available, the drug contains various biologically active substances. Indications for use In the complex therapy of mild functional disorders of the central nervous system (neurasthenia and sleep disorders). Dosage and administration For adults, the drug is prescribed 2 tablets 3 times a day. The drug is taken without chewing, with a small amount of liquid. If nausea occurs, the drug should be taken with food. If necessary, a single dose is increased to 3 tablets. In case of occurrence of undesirable reactions from the nervous system (drowsiness, dizziness) – appoint 1 tablet 3 times a day. The interval between doses of the drug is 8 hours. The duration of treatment depends on the form and severity of the symptoms of the disease, the nature of concomitant therapy, the effect of treatment achieved and is determined by the doctor. Use during pregnancy and lactation It is not recommended to prescribe the drug during pregnancy or lactation. Precautions The composition of the drug includes lactose. Before taking the drug, you need to consult a doctor. Due to the gradual development of the effect, the drug is not recommended for use in cases of urgent need to reduce the symptoms of mental arousal and sleep disturbances. If the symptoms persist while taking the drug or if the condition worsens, you should consult a doctor. Patients with rare hereditary disorders of carbohydrate metabolism, in particular galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption syndrome, should not take this medicinal product. When using the drug, patients, especially with fair skin, should avoid prolonged exposure to ultraviolet radiation (sunbathing, solarium, diathermy). Patients with gastroesophageal reflux (heartburn) may experience increased heartburn. Use the drug with caution in patients with changes in blood pressure and diabetes mellitus. It is necessary to control blood pressure and blood glucose levels. Do not take with alcohol. Interaction with other drugs While taking the drug Sedavit, the appointment of synthetic sedatives is contraindicated. If you are taking other medicines at the same time, you need to consult a doctor. The drug enhances the effect of substances that have a sedative effect on the central nervous system, as well as alcohol. Mutual weakening of the action of levodopa and pyridoxine hydrochloride is possible. The simultaneous use of cycloserine, hydralazine, isoniazid, penicillamine and oral contraceptives causes an increased need for pyridoxine. St. John’s wort perforated can cause the induction of cytochrome P450 isoenzymes 3A4, 1A2 and 2C9, which can cause a decrease in the effect of other drugs that are simultaneously taken and metabolized by these isoenzymes. In this regard, the simultaneous use of the drug with: – indinavir or other antiretroviral drugs is not recommended; – cyclosporine, digoxin, theophylline, irinotecan, tacrolimus, lipid-lowering agents (simvastatin and others), fexofenadine, tricyclic antidepressants (amitriptyline, nortriptyline), antiepileptic drugs (carbamazepine, phenobarbital, phenytoin), selective serotonin reuptake inhibitors (citalopramamine, flupramamine, sertraline, paroxetine), buspirone, as well as triptans (sumatriptan, naratriptan, zolmitriptan) and antihypertensive calcium channel blockers; – warfarin and other anticoagulants – coumarin derivatives; – oral contraceptives (due to a decrease in the effectiveness of contraceptives with the occurrence of irregular bleeding, an unwanted pregnancy cannot be ruled out). Not recommended for use with cardiac glycosides. Diuretics – when combined with pyridoxine, the effect of diuretics is enhanced. Sleeping pills and sedatives – when combined with pyridoxine, the hypnotic effect is reduced. Antiparkinsonian drugs – when combined with pyridoxine, the effectiveness of drugs for the treatment of Parkinson’s disease decreases. Corticosteroids – when combined with pyridoxine, the amount of vitamin B6 in the body decreases. With the simultaneous use of nicotinic acid with antithrombotic agents or acetylsalicylic acid, there is a risk of bleeding. The use with antihypertensive drugs leads to an increase in arterial hypotension, with antidiabetic drugs – to a decrease in the hypoglycemic effect of the latter. Use with lipid-lowering drugs increases the risk of developing toxic effects of the drug, with antispasmodics – the effect of antispasmodics is enhanced. Simultaneous use with methyldopa leads to a significant decrease in blood pressure, with probenecid – a decrease in the effect of probenecid. It is possible to enhance the photosensitizing effect of other drugs that have a photosensitizing effect (for example, sulfonamides, antibiotics of the tetracycline group and fluoroquinolones). ContraindicationsIncreased individual sensitivity to the components of the drug, depression and conditions accompanied by depression of the central nervous system, bronchial asthma, spasmophilia, a tendency to laryngospasm, severe arterial hypotension, bradycardia, myasthenia gravis, peptic ulcer of the stomach and duodenum, cholelithiasis, gastroesophageal reflux , coronary heart disease, liver disease, hyperuricemia, gout, decompensated diabetes mellitus, urolithiasis. Simultaneous reception with cyclosporine, tacrolimus, amprenavir, indinavir and other protease inhibitors; irinotecan and warfarin, children under 18; period of pregnancy and lactation. Composition 1 tablet contains: active ingredients: thick sedavita extract* – 170.0 mg, vitamin B6 – 3.0 mg, vitamin PP – 15.0 mg; excipients: potato starch; croscarmellose sodium; lactose monohydrate; cellulose microcrystalline; calcium stearate. * – 1 g of thick sedavite extract contains: at least 0.01 g of flavonoids extracted with ethanol 35% (1:4.5) from a mixture of: valerian rhizomes with roots (2 parts), hawthorn fruits (2 parts), St. John’s wort herb (1 part), peppermint leaves (2 parts), hop cones (2 parts). OverdoseSymptoms: increased side effects. Later, these symptoms may be accompanied by numbness, joint pain, and a feeling of heaviness in the stomach. Symptoms of an overdose of nicotinamide may also appear: dizziness, convulsions, tremor, sweating, cough, skin rash, arterial hypotension. Symptoms characteristic of peripheral neuropathy. Treatment: drug withdrawal, symptomatic therapy. Side effect The following undesirable effects are possible: Allergic reactions, including hyperemia, rash, itching, swelling, urticaria, anaphylactic reactions, including anaphylactic shock. From the side of the central and peripheral nervous system: drowsiness, fatigue, dizziness, depressed emotional state, agitation, headache, paresthesia, weakness, decreased performance. From the digestive tract: nausea, pain and cramps in the abdomen, vomiting, heartburn, increased gastric secretion, impaired bowel function (diarrhea, constipation). From the cardiovascular system: bradycardia, lowering blood pressure, tachycardia, arrhythmia. From the skin: photosensitivity in sensitive people, dermatitis, dry skin. From the musculoskeletal system: numbness of the limbs, muscle weakness. On the part of metabolism: with prolonged use in high doses – a decrease in glucose tolerance. Deviations of biochemical parameters from the norm: increased levels of aspartate aminotransferase (ACT), lactate dehydrogenase (LDH), alkaline phosphatase, blood glucose, hyperuricemia. In the event of adverse reactions, including those not listed in this leaflet, you should stop using the drug and consult a doctor. Storage conditions In a place protected from light and moisture at a temperature not exceeding 25 ° C. Keep out of reach of children. Buy Sedavit tablets No. 10×2 Price for Sedavit tablets No. 10×2 Instructions for use for Sedavit tablets No. 10×2