Sedavit oral solution 100ml №1

Name:
Sedavit rr d / vn.prim. 100 ml in pack No. 1
Description:
Light brown to brown liquid. During storage, the formation of a slight precipitate is allowed. The main active ingredient Sedavit extract liquid Release form In jars or bottles of 100 ml in package No. 1. Each jar or bottle, along with instructions for use and a dispenser, is put into a pack of cardboard boxes. Dosage 100 ml in pack No. 1 Pharmacodynamics A complex extract for the drug Sedavit is obtained from rhizomes with valerian roots, hawthorn fruits, St. John’s wort, peppermint leaves, hop cones. The pharmacological action of the drug is due to the properties of the components that make up its composition. Biologically active substances of the extracts have a sedative effect, facilitate the onset of sleep. Vitamins (pyridoxine hydrochloride (vitamin B6) and nicotinamide (vitamin PP)) are involved in the processes of tissue respiration, fat and carbohydrate metabolism. Pharmacokinetics No data available, the drug contains various biologically active substances. Indications for use In the complex therapy of mild functional disorders of the central nervous system (neurasthenia and sleep disorders). Method of administration and doses: For adults, the drug is prescribed 1 scoop (5 ml) 3 times a day. If nausea occurs, the drug should be taken with food. If necessary, a single dose is increased to 2 scoops (10 ml). In the event of adverse reactions from the nervous system (drowsiness, dizziness) – appoint 1/2 scoop (2.5 ml) in the morning and afternoon, 1 scoop (5 ml) at night. The interval between doses of the drug is 8 hours. The duration of treatment depends on the characteristics of the disease, the tolerance of the drug, the effect achieved, and is determined by the doctor. Use during pregnancy and lactation Do not use the drug during pregnancy or lactation. Precautions The composition of the drug includes sorbitol (E 420). Patients with hereditary fructose intolerance or glucose-galactose malabsorption should not take this medicinal product. Due to the content of sorbitol, it may have a slight laxative effect. Energy value 2.6 kcal/g sorbitol. The medicinal product contains at least 27% ethanol, i.e. 1.368 g per single dose (5 ml) and 2.736 g per single dose (10 ml). Due to the content of ethyl alcohol, the drug is contraindicated in patients with liver disease, alcoholism, epilepsy, traumatic brain injury and other brain diseases with a decrease in the convulsive threshold, pregnant and lactating women, children under 18 years of age. Before taking the drug, you need to consult a doctor. Due to the gradual development of the effect, the drug is not recommended for use in cases of urgent need to reduce the symptoms of mental arousal and sleep disturbances. If the symptoms persist while taking the drug or if the condition worsens, you should consult a doctor. When using the drug, patients, especially with fair skin, should avoid exposure to ultraviolet radiation (sunbathing, solarium, diathermy). Patients with gastroesophageal reflux (heartburn) may experience increased heartburn. Use the drug with caution in patients with unstable blood pressure and diabetes mellitus. It is necessary to control blood pressure and blood glucose levels. Do not take with alcohol. Interaction with other drugs While taking the drug Sedavit, the appointment of synthetic sedatives is contraindicated. If you are taking other medicines at the same time, you need to consult a doctor. The drug enhances the effect of substances that have a sedative effect on the central nervous system, as well as alcohol. Mutual weakening of the action of levodopa and pyridoxine hydrochloride is possible. The simultaneous use of cycloserine, hydralazine, isoniazid, penicillamine and oral contraceptives causes an increased need for pyridoxine. St. John’s wort, perforated, can cause the induction of cytochrome P450 isoenzymes 3A4, 1A2 and 2C9, which can cause a decrease in the effect of other drugs that are simultaneously taken and metabolized by these isoenzymes. In this regard, the simultaneous use of the drug with: – indinavir or other antiretroviral drugs is not recommended; -cyclosporine, digoxin, theophylline, irinotecan, tacrolimus, lipid-lowering agents (simvastatin and others), fexofenadine, tricyclic antidepressants (amitriptyline, nortriptyline), antiepileptic drugs (carbamazepine, phenobarbital, phenytoin), selective serotonin reuptake inhibitors (citalopoxamine, fluvopramamine, sertraline, paroxetine), buspirone, as well as triptans (sumatriptan, naratriptan, zolmitriptan) and antihypertensive calcium channel blockers; – warfarin and other anticoagulants – coumarin derivatives; – oral contraceptives (due to a decrease in the effectiveness of contraceptives with the occurrence of irregular bleeding, an unwanted pregnancy cannot be ruled out). Not recommended for use with cardiac glycosides. Diuretics – when combined with pyridoxine, the effect of diuretics is enhanced. Sleeping pills and sedatives – when combined with pyridoxine, the hypnotic effect is reduced. Antiparkinsonian drugs – when combined with pyridoxine, the effectiveness of drugs for the treatment of Parkinson’s disease decreases. Corticosroids – when combined with pyridoxine, the amount of vitamin B6 in the body decreases. With the simultaneous use of nicotinic acid with antithrombotic agents or acetylsalicylic acid, there is a risk of bleeding. Use with antihypertensive drugs leads to increased arterial hypotension. Use with lipid-lowering agents increases the risk of developing toxic effects of the drug, with antispasmodics – the effect of antispasmodics is enhanced. Simultaneous use with methyldopa leads to a significant decrease in blood pressure, with probenecid – a decrease in the effect of probenecid. It is possible to enhance the photosensitizing effect of other drugs that have a photosensitizing effect (for example, sulfonamides, tetracycline antibiotics and fluoroquinolones). ContraindicationsIncreased individual sensitivity to the components of the drug, depression and conditions accompanied by depression of the central nervous system, bronchial asthma, spasmophilia, a tendency to laryngospasm, severe arterial hypotension, bradycardia, myasthenia gravis, peptic ulcer of the stomach and duodenum, cholelithiasis, gastroesophageal reflux , coronary heart disease, liver disease, hyperuricemia, gout, decompensated diabetes mellitus, urolithiasis. Simultaneous reception with cyclosporine, tacrolimus, amprenavir, indinavir and other protease inhibitors; irinotecan and warfarin, children under 18; period of pregnancy and lactation. Composition 1 ml of the medicinal product contains: active ingredients: Sedavit liquid extract (extrahept – ethanol 35% v / v) (1: 4.5) – 0.94 ml from a mixture of medicinal plant materials: valerian rhizomes with roots, hawthorn fruits, St. John’s wort herb , peppermint leaves, hop cones; Pyridoxine hydrochloride (Vitamin B6) – 0.60 mg; Nicotinamide (Vitamin PP) – 3.00 mg; excipient: sorbitol (E 420) – 100 mg. The content of ethanol in the finished medicinal product is not less than 27.0%. OverdoseSymptoms: increased side effects; feeling depressed and sleepy. Later, these symptoms may be accompanied by nausea, muscle weakness, numbness, joint pain and a feeling of heaviness in the stomach, paresthesia. Symptoms of an overdose of nicotinamide may also appear (tachycardia, headache, dizziness, convulsions, tremor, nausea, vomiting, diarrhea, excessive sweating, cough, skin rash, arterial hypotension). In case of overdose, you should consult a doctor. Treatment: drug withdrawal. Symptomatic therapy. Side effect The following undesirable effects are possible: Allergic reactions, including hyperemia, rash, itching, swelling, urticaria, anaphylactic reactions, including anaphylactic shock. From the side of the central and peripheral nervous system: drowsiness, fatigue, dizziness, depressed emotional state, agitation, headache, paresthesia, weakness, decreased performance. From the digestive tract: nausea, pain and cramps in the abdomen, vomiting, heartburn, increased gastric secretion, impaired bowel function (diarrhea, constipation). From the cardiovascular system: bradycardia, lowering blood pressure, tachycardia, arrhythmia. From the skin: photosensitivity in sensitive people, dermatitis, dry skin. From the musculoskeletal system: numbness of the limbs, muscle weakness. On the part of metabolism: with prolonged use in high doses – a decrease in glucose tolerance. Deviations of biochemical parameters from the norm: increased levels of aspartate aminotransferase (ACT), lactate dehydrogenase (LDH), alkaline phosphatase, blood glucose, hyperuricemia. In the event of adverse reactions, including those not listed in this leaflet, you should stop taking the drug and consult a doctor. Storage conditionsIn the original packaging at a temperature not exceeding 25°C. Keep out of the reach of children. After opening, store no more than 28 days. Buy Sedavit oral solution 100ml No. 1 Price for Sedavit oral solution 100 ml No. 1