Name:
Salbutamol. Release form aerosol for inhalation dosed Dosage 100 mcg / 1 dose 200 doses Quantity per package: 1 pc. Producer Jevim Pharmaceutical MNN Salbutamol FTHBeta2-adrenergic agonist selective
Description:
Homogeneous suspension of white or slightly yellow color, in a pressurized container with a dosing device and a spray nozzle. Composition Each dose contains: Salbutamol 100 mcg Excipients: Oleic acid, Anhydrous ethanol, 1,1,1,2-Tetrafluoroethane. Pharmacotherapeutic group Bronchodilator – β2-adrenergic agonist. ATX code: R03AC02. Indications for use Short-term (from 4 to 6 hours) expansion of the bronchi with a rapid onset (within about 5 minutes) with airway obstruction. Relief of asthma attacks in diseases accompanied by airway obstruction, such as bronchial asthma. Prevention of attacks of bronchospasm associated with exposure to an allergen or caused by physical activity. In the complex therapy of patients with bronchial asthma. Method of application and doses Salbutamol is an aerosol that is intended only for inhalation use through the mouth. For patients who find it difficult to synchronize breathing with the use of an inhaler, it is recommended to additionally use a spacer – a device to facilitate the inhalation of inhaled drugs. Adults (including elderly patients) For relief of exacerbation of asthma symptoms, including acute bronchospasm, 1 inhalation (100 mcg) can be used as the minimum starting dose. If necessary, the dose can be increased to 200 mcg (2 inhalations). Prophylactically 10-15 minutes before physical activity or expected contact with allergens, 200 mcg (2 inhalations) is used. With long-term maintenance therapy, it is recommended to use 200 mcg (2 inhalations) 4 times a day. Children aged 4 to 12 years For the relief of acute bronchospasm, 1 inhalation (100 mcg) is used. If necessary, the dose can be increased to 200 mcg (2 inhalations). For children over 12 years of age, doses are used as for adults. Prophylactically 10-15 minutes before physical activity or expected contact with allergens, 200 mcg (2 inhalations) is used. With long-term maintenance therapy, it is recommended to use 200 mcg (2 inhalations) 4 times a day. The total daily dose of salbutamol should not exceed 800 micrograms (8 inhalations). An increased need for beta-2-agonists may indicate a worsening of the course of bronchial asthma. Under these conditions, the patient’s treatment regimen should be reviewed and the need for GCS therapy should be considered. Preparation for the first application. Before using the container for the first time, remove the protective cap from the inhaler nozzle. Then shake the container well with vertical movements, turn the container upside down with the inhaler nozzle and make two sprays into the air to ensure adequate operation. If the use is interrupted for several days, one spray into the air should be done after thoroughly shaking the container. Application: Remove the protective cap from the inhaler nozzle. Make sure that the inner and outer surfaces of the inhaler nozzle are clean. Shake the container well with vertical movements. Turn the container upside down with the inhaler nozzle, hold the container vertically between the thumb and middle and index fingers so that the thumb is under the inhaler nozzle. Exhale as deeply as possible, then place the inhaler nozzle in your mouth between your teeth and cover it with your lips, and do not bite at the same time. Starting to inhale through the mouth, press the top of the container to spray the drug, while continuing to inhale slowly and deeply. Hold your breath, remove the inhaler nozzle from your mouth and remove your finger from the top of the container. Continue to hold your breath for as long as possible. If you need to perform the next inhalation, wait about 30 seconds, holding the inhaler upright, then follow steps 2-6. Close the inhaler nozzle with a protective cap. IMPORTANT: Follow steps 4, 5 and 6 slowly. It is important to start inhaling as slowly as possible just before spraying. The first few times you should practice in front of a mirror. If a “cloud” appears on the sides of the mouth, you must start again from point 2. Cleaning: The inhaler nozzle should be cleaned at least once a week. Remove the protective cap from the inhaler nozzle, and remove the inhaler nozzle from the container. Thoroughly wash the inhaler nozzle and protective cap under warm running water. Dry the inhaler nozzle and protective cap thoroughly inside and out. Put the inhaler nozzle on the container and the valve stem, close the free opening of the inhaler nozzle with a protective cap. DO NOT submerge the container in water! Children. Applied to children aged 4 years. Adverse reactions The adverse reactions listed below are classified by organs and systems, as well as by frequency of occurrence: very often (3 1/10), often (3 1/100 and <1/10), infrequently (3 1/1000 and <1 / 100), rarely (3 1/10 000 and < 1/1000), very rarely (< 1/10 000), including isolated cases, the frequency is unknown. On the part of the immune system Very rarely: hypersensitivity reactions, including angioedema, urticaria, bronchospasm, arterial hypotension and collapse. On the part of metabolism, metabolism Rare: hypokalemia. Potentially, the use of beta-2-agonists can cause severe hypokalemia. Neurological disorders Common: tremor, headache. Very rare: hyperactivity. Cardiac disorders Often: tachycardia. Uncommon: palpitations. Very rare: cardiac arrhythmias, including atrial fibrillation, supraventricular tachycardia and extrasystole. Frequency unknown: myocardial ischemia. Vascular disorders Rare: peripheral vasodilation. Respiratory, thoracic and mediastinal disorders Very rare: paradoxical bronchospasm. Gastrointestinal disorders Uncommon: irritation of the mucous membranes of the oral cavity and pharynx. From the musculoskeletal system and connective tissue Uncommon: muscle cramps. ContraindicationsHypersensitivity history to any component of the drug. Although salbutamol in the form of a solution for injection and sometimes in the form of tablets is used in preterm labor, salbutamol in the form of an aerosol for inhalation is not used for these indications. Salbutamol is not used in case of threatened abortion. Overdose The most common signs and symptoms of salbutamol overdose are transient changes pharmacologically induced by beta-agonists, such as tachycardia, tremor, hyperactivity, and metabolic disturbances, including hypokalemia. As a result of an overdose of salbutamol, hypokalemia may occur, so it is necessary to control the level of potassium in the blood serum. Cases of lactic acidosis have been reported with high therapeutic doses or overdose of short beta-agonists, so serum lactate levels should be checked and metabolic acidosis monitored accordingly, especially in the case of persistent or progressive rapid breathing, despite improvement in symptoms of bronchospasm, such as stridor breath. Interaction with other drugs and other types of interactions Salbutamol should not be administered together with non-selective beta-blockers such as propranolol. Salbutamol is not contraindicated for the appointment of patients who are treated with MAO inhibitors. Use during pregnancy and lactationAccording to animal studies, salbutamol has reproductive toxicity. The safety of use in pregnant women has not been established. Controlled clinical studies on the use of salbutamol in pregnant women have not been conducted. There have been sporadic reports of various congenital malformations in utero, including cleft palate, limb defects, and cardiac abnormalities. Some women took many other medicines during pregnancy. Salbutamol should not be taken during pregnancy, use is possible only in case of emergency. Salbutamol is likely to pass into breast milk, so it should be used with caution in women who are breastfeeding. Whether the presence of salbutamol in breast milk has a harmful effect on the newborn/infant is unknown, therefore its use during lactation should be limited to cases where the benefit to the woman will outweigh the possible risk to the baby. Precautions In order to optimally get the drug into the lungs of the patient, his technique for inhaling the drug should be checked. Patients should be warned about the possibility of experiencing a different taste than when using the previous inhaler. Sudden and progressive worsening of asthma is a life-threatening condition that requires the initiation of treatment or an increase in the dose of corticosteroids used. Patients at risk are advised to monitor the maximum expiratory flow rate daily. Bronchodilator drugs should not be the only or main drug in the treatment of patients with severe or unstable bronchial asthma. The condition of such patients should be regularly monitored, including lung tests, since severe bronchial asthma is a life-threatening disease, and for the treatment of such patients, the issue of prescribing inhaled and / or oral corticosteroids should be decided. If the effect of the usual dose of salbutamol becomes less effective or the duration of its action decreases (less than 3 hours), the patient should consult a doctor. An increase in the dose or frequency of use of the drug is carried out only by a doctor. An increase in the need for bronchodilators, especially inhaled beta-2-agonists, to control asthma symptoms indicates an exacerbation of the disease. In these cases, the treatment plan should be reviewed and the question of prescribing large doses of inhaled corticosteroids or a course of oral corticosteroids should be considered. A severe exacerbation of asthma should be treated as usual. Sympathomimetics, including salbutamol, affect the cardiovascular system. According to post-registration use and published data, there is evidence of rare cases of myocardial ischemia associated with the use of salbutamol. Patients with heart disease (for example, coronary heart disease, arrhythmias, or severe heart failure) and who are treated with salbutamol should seek medical attention if they develop chest pain or other symptoms that indicate an exacerbation of heart disease. Attention should be paid to the assessment of symptoms such as shortness of breath and chest pain, which can be due to both heart disease and diseases of the respiratory system. With caution, salbutamol should be prescribed to patients with thyrotoxicosis. Severe hypokalemia can result from treatment with beta-2 agonists. This is mainly observed when using parenteral forms or a nebulizer. Particular attention is paid to patients with acute severe bronchial asthma, since hypokalemia can be potentiated by the concomitant use of xanthine derivatives, steroids, diuretics and hypoxia. In this situation, it is recommended to check the level of potassium in the blood serum. Salbutamol is used with caution in the treatment of patients receiving large doses of other sympathomimetics. Like other beta-adrenergic agonists, salbutamol can lead to reversible metabolic changes, such as an increase in blood sugar levels. Compensation for such changes in patients with diabetes mellitus is not always possible, so there are separate reports of the development of ketoacidosis in such patients. Concomitant use of corticosteroids may exacerbate this condition. As with the use of other inhalation drugs, paradoxical bronchospasm is possible with an immediate increase in dyspnea after the use of the drug. In this case, it is necessary to immediately prescribe alternative forms of the drug or other fast-acting inhaled bronchodilators. Salbutamol should be discontinued immediately, the patient assessed and, if necessary, another rapid-acting bronchodilator be prescribed on an ongoing basis. The ability to influence the reaction rate when driving motor transport or operating other mechanisms There are no data on the effect, in case of adverse reactions from the nervous system (tremor), driving or working with mechanisms should be limited. Conditions and shelf lifeAt a temperature not higher than 25 °C. Avoid exposure to direct sunlight. Do not freeze. Shelf life - 3 years. Do not use after the expiry date stated on the package. Keep out of the reach of children. Conditions of leave By doctor's prescription. Packaging An aluminum can containing 200 or 400 doses of 100 mcg of Salbutamol, with a dosing device and a spray nozzle, is placed with instructions for use in a secondary package - a cardboard box. inhalation dosed 100mcg/dose 200 doses №1
Salbutamol aerosol for inhalation dosed 100mcg/dose 200 doses №1
$20.00
SKU: 146282
Category: Asthma treatment
INN | Salbutamol |
---|---|
The code | 146 282 |
Barcode | 4 810 155 003 421 |
Dosage | 100mcg/dose 200dose |
Active substance | Salbutamol |
Manufacturer | Jevim Pharmaceutical(Shandong) Co.Ltd.China, pack.JSC Ekzon, Belarus |
Be the first to review “Salbutamol aerosol for inhalation dosed 100mcg/dose 200 doses №1” Cancel reply
Related products
Asthma treatment
Pulmovent Combi solution for inhalation (0.5mg+0.25mg)/ml 20ml №1
$20.00
Asthma treatment
Salbutamol aerosol for inhalation dosed 100mcg/dose 200 doses №1
$20.00
$28.00
Reviews
There are no reviews yet.