Revalon 600 tablets p/o №10×3

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Revalon 600 tabl.po in box. pack No. 10×3
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Coated tablets, from gray to brown with dark and light patches, oval, with a biconvex surface, with a risk. The main active ingredientValerian rhizomes with roots Release formcoated tablets Dosage600 mg Pharmacological propertiesPharmacodynamicsValerian root preparations have a sedative effect, facilitate the onset of sleep and improve the quality of sleep. These effects cannot be explained by the action of any one component of valerian. Some of the mechanisms of action that cause these clinical effects have been identified for various components of valerian root (sesquiterpenoids, lignans, flavonoids) and include effects on the GABA system, A1 adenosine receptors and 5-HT1A receptors. The sedative effect when using valerian preparations manifests itself slowly, but rather stably and fully develops only with a systematic course of treatment. Pharmacokinetics The pharmacokinetics of valerian has not been studied enough, due to the impossibility of accurately identifying the active principle of the drug. Indications for use Apply with increased nervous excitability (neurasthenia) and sleep disorders. Dosage and administrationAdults and children over 12 years old With increased nervous excitability (neurasthenia): 1 tablet (600 mg) 1-2 times a day. For sleep disorders: 1 tablet 0.5-1 hour before bedtime, if necessary, it is recommended to pre-administer the drug (1 tablet) in the evening. In cases of urgent need to reduce the symptoms of mental arousal and sleep disorders, the use of valerian preparations is not recommended due to the gradual development of the effect. The recommended duration of treatment is 2-4 weeks. If symptoms persist or worsen after 2 weeks of continuous use, seek medical advice. The duration of the course of treatment is determined by the doctor, taking into account the characteristics of the disease, the effect achieved and the tolerability of the drug. Features of use in patients with impaired liver and / or kidney function: no information available. Use during pregnancy and lactation The safety of use during pregnancy and lactation has not been established. Due to the lack of sufficient data, it is not recommended to use during pregnancy and lactation. Precautions Due to the gradual development of the effect, valerian preparations are not recommended for use in cases of urgent need to reduce the symptoms of mental arousal and sleep disturbances. If within 2 weeks of continuous use of the drug, the symptoms of the disease persist or worsen, you should consult a doctor. Interaction with other drugs Data on interactions with other drugs are limited. No clinically significant interactions have been observed with drugs metabolized by CYP 2D6, CYP 3A4/5, CYP 1A2, or CYP 2E1. The combination of valerian preparations with synthetic sedatives requires prior consultation with a doctor and supervision of a doctor during treatment. Contraindications Hypersensitivity to valerian or auxiliary components of the drug, pregnancy, lactation, children under 12 years of age. Composition of the active substance: thick valerian extract (with the content of esters of carboxylic acids in terms of ethyl ester of valerenic acid – not less than 9.0 mg) ((2.36-2.73) : (0.73-1.27) from rhizomes with valerian roots, extractant – ethyl alcohol 40% (v / v)) – 600 mg; excipients: talc, croscarmellose sodium, microcrystalline cellulose, magnesium stearate, calcium hydrogen phosphate dihydrate, Opadry (including hypromellose, triacetin, talc ). With a single dose of an excessively high dose (about 20 g of valerian root), it is possible to develop spastic abdominal pain, chest tightness, dizziness, general weakness, hand tremors and dilated pupils. In case of overdose, you should consult a doctor. With a single dose of a high dose, it is recommended to induce vomiting, gastric lavage (no later than 2 hours after taking the drug). With prolonged use of the drug in high doses, drug withdrawal is recommended. There is no specific antidote. Symptomatic therapy. Side effects Possible development of allergic reactions (skin rash, itching, hyperemia, swelling of the skin); the occurrence of headache, general weakness, decreased performance, drowsiness, irritability, anxiety, gastrointestinal disorders (nausea, abdominal pain). Large doses can lead to bradycardia and arrhythmia, as well as decreased intestinal motility (constipation). In case of adverse reactions, including those not listed in the instructions for use, you should consult a doctor. Storage conditions In a place protected from light and moisture, at a temperature not exceeding 25 ° C. Keep out of the reach of children. Buy Revalon 600 tablets p/o No. 10×3 Price for Revalon 600 tablets p/o No. 10×3