Relief rectal suppositories 5mg №6×2

DescriptionSuppositories rectal from almost white to light yellow color, opaque, in the form of a torpedo. The main active ingredient Shark liver oil + phenylephrine Release form Suppositories Pharmacological properties Phenylephrine hydrochloride is an alpha-adrenergic agonist, has a local vasoconstrictive effect, which helps to reduce exudation, tissue swelling and itching in the anorectal region. Indications for use As a symptomatic agent in the complex therapy of hemorrhoids, anal fissures. Dosage and administration Use the drug after hygiene procedures. Enter into the rectum one suppository up to 4 times a day (in the morning, at night and after each bowel movement). The duration of the course of treatment is determined by the doctor, taking into account the characteristics of the disease, the tolerability of the drug and the effect achieved. Use during pregnancy and lactation The drug is not recommended for use by women during pregnancy and lactation. Precautions for patients with arterial hypertension, cardiovascular disease, thyroid disease, angle-closure glaucoma, diabetes mellitus, liver disease, pancreas, urination disorders (for example, in the case of prostatic hyperplasia), the drug can be used only after consulting a doctor, during treatment medical supervision is necessary. Before prescribing the drug, the doctor should clarify the allergic history, including allergic reactions to other sympathomimetic drugs. Do not use the suppository if the protective plastic cover is damaged or missing. In case of heavy bloody discharge from the anus or the absence of a therapeutic effect when using the drug, you should consult a doctor. Due to the content of methyl parahydroxybenzoate and propyl parahydroxybenzoate, it may cause allergic reactions, including delayed reactions. Interaction with other drugs The drug should not be used simultaneously with other vasoconstrictors (regardless of the route of administration of the latter), as well as with antihypertensive drugs (β-blockers). Atropine sulfate blocks the reflex bradycardia caused by phenylephrine and increases the vasopressor response to phenylephrine. Simultaneous use of phenylephrine with ?-blockers can lead to arterial hypertension and severe bradycardia with possible heart block. Caution should be exercised when using Relief together with thyroid hormones, drugs that affect cardiac conduction (cardiac glycosides, antiarrhythmic drugs). With simultaneous use with drugs that cause potassium excretion (for example, with diuretics such as furosemide), hypokalemia may increase and sensitivity to vasopressor drugs such as phenylephrine may decrease. The simultaneous use of phenylephrine and other sympathomimetic drugs can lead to additional stimulation of the central nervous system, which is accompanied by agitation, irritability, insomnia, and a seizure may develop. Relief should not be used simultaneously or within 14 days after stopping treatment with MAO inhibitors. Contraindications Hypersensitivity to the components of the drug, severe arterial hypertension, tachysystolic cardiac arrhythmias, decompensated heart failure, cardiac conduction disorders, severe renal and / or liver failure, thyrotoxicosis, acute pancreatitis, thromboembolism (including previously transferred), granulocytopenia, simultaneous use with monoamine oxidase (MAO) inhibitors or within 14 days after stopping treatment with MAO inhibitors. Active ingredient (1 suppository contains): phenylephrine hydrochloride 5 mg (0.25%). Excipients: cocoa butter, corn starch, shark liver oil, methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216). Overdose In case of a significant excess of the recommended doses, there may be a tendency to hypercoagulability. In case of an overdose, the following disorders are possible: arterial hypertension, pain and discomfort in the heart area, palpitations, respiratory disorders, non-cardiogenic pulmonary edema, agitation, convulsions, sleep disturbances, anxiety, irritability, psychoses with hallucinations, general weakness, anorexia, nausea, vomiting, oliguria, urination disorders, redness of the face, feeling of coldness in the extremities, paresthesia, hyperglycemia, hypokalemia, decreased blood flow to vital organs, which can lead to poor blood supply to the kidneys, metabolic acidosis, increased load on the heart due to an increase in total peripheral resistance. Treatment is symptomatic. Side effects The following adverse reactions are possible: From the side of the cardiovascular system: reflex bradycardia, cardiac arrhythmias, increased blood pressure. On the part of the immune system: hypersensitivity reactions, including cross-type reactions in case of allergic reactions to other sympathomimetic drugs, which can manifest as skin rash, itching, angioedema, contact dermatitis. From the nervous system: dizziness, nervousness, headache, tremor, insomnia, anxiety, feeling hot flashes. From the skin and subcutaneous tissues: contact dermatitis, hyperemia, skin rash, itching, swelling, pain, burning. In the event of adverse reactions, including those not listed in the instructions for use, it is necessary to stop using the drug and consult a doctor. Storage conditions At a temperature not exceeding 25 ° C, out of the reach of children. Buy Relief rectal suppositories 5mg No. 6×2 Price for Relief rectal suppositories 5mg No. 6×2