Phosphogliv capsules №10х5

Name:
Phosphogliv caps. in box No. 10×5
Description:
hard gelatin capsules No. 0, capsule body – orange, cover – black. The main active ingredient Phospholipids + glycyrrhizic acid Release formCapsules Pharmacological propertiesCombined agent. It has a membrane-stabilizing, hepatoprotective effect. Phosphatidylcholine (the active substance of phospholipids) is the main structural element of cellular and intracellular membranes, capable of restoring their structure and functions when damaged, providing a cytoprotective effect. It normalizes protein and lipid metabolism, prevents the loss of enzymes and other active substances by hepatocytes, restores the detoxifying function of the liver, inhibits the formation of connective tissue, reducing the risk of fibrosis and cirrhosis of the liver. Glycyrate (glycyrrhizic acid and salts) has an anti-inflammatory effect, inhibits the reproduction of viruses in the liver and other organs by stimulating the production of interferons, increasing phagocytosis, and increasing the activity of natural killer cells. It has a hepatoprotective effect due to antioxidant and membrane stabilizing activity. Potentiates the action of endogenous glucocorticosteroids, providing anti-inflammatory and anti-allergic effects in non-infectious liver lesions. With skin lesions, due to the membrane-stabilizing and anti-inflammatory action of the components, it limits the spread of the process and contributes to the regression of the disease. Pharmacokinetics The components of the drug are well absorbed in the intestine both in the form of whole molecules and bioactive hydrolysis products (unsaturated fatty acids, choline, glycyrrhetic acid), which, after being absorbed through the intestinal wall, easily penetrate into the liver, lungs, skin and other organs. Indications for use As part of the complex therapy of viral hepatitis (acute and chronic), fatty liver degeneration (hepatosis), other liver damage (drug, alcohol, toxic), liver cirrhosis. Dosage and administration Take orally, during meals, drinking a small amount of liquid. Adults over 18 years: 1-2 capsules 3-4 times a day. Skipping the next dose of the drug If one or more doses are missed, the drug should be resumed as usual, without doubling the dose. Use during pregnancy and lactation Phosphogliv is contraindicated for use during pregnancy and during breastfeeding. Therefore, if you need to take Phosphogliv, breastfeeding should be stopped. PrecautionsUse with caution in patients with portal hypertension, in patients with arterial hypertension. Application in childhood The use of the drug is allowed from 18 years of age. Interaction with other drugs Simultaneous use with thiazide diuretics, cardiac glycosides, corticosteroids, stimulant laxatives or other drugs that can increase electrolyte imbalance is not recommended. Contraindications Hypersensitivity to the components of the drug, antiphospholipid syndrome, pregnancy, lactation, children under 18 years of age. Composition Active substances: Phospholipids (in terms of phosphatidylcholine) – 65 mg, sodium glycyrrhizinate (trisodium salt of glycyrrhizic acid) – 35 mg. Excipients: microcrystalline cellulose – 141.2 mg, calcium carbonate – 204.7 mg, calcium stearate – 0.9 mg, talc – 7.7 mg, colloidal silicon dioxide (aerosil) – 5.5 mg. The composition of the capsule shell (hard gelatin capsules No. 0): titanium dioxide (E 171), iron oxide black (E 172), sunset yellow dye (E 110), acetic acid, gelatin. Overdose Glycyrrhizic acid, which is part of the drug, in large doses can cause a pseudocorticosteroid effect, which is an increase in the level of glucocorticosteroids and mineralocorticoids in the blood. This leads to a delay in the body of sodium and fluid with a simultaneous decrease in the content of potassium, and, as a result, to an increase in blood pressure and edema. Treatment: in case of overdose, treatment is symptomatic. Side effects Possible skin rash (with increased individual sensitivity), which disappears after discontinuation of the drug. If daily doses are exceeded, sodium and fluid retention, edema, increased blood pressure, and hypokalemia may occur. When these symptoms appear, depending on their severity, it is necessary to reduce the dose of the drug and / or prescribe spironolactone 50-100 mg per day. Storage conditions Store at a temperature no higher than . Keep out of the reach of children. Store in original packaging. Buy Phosphogliv capsules No. 10×5 Price for Phosphogliv capsules No. 10×5 Instructions for use for Phosphogliv capsules No. 10×5