Neurobeks tablets p / o in jars No. 90 No. 1

Name Neurobeks tablets p / o in bank No. 90 in pack No. 1 The main active ingredient is Pyridoxine + thiamine + cyanocobalamin. Release form Tablets. Pharmacological action Neurobex® is a combined preparation containing B vitamins. They are part of enzymes that catalyze the metabolism of carbohydrates, fats and proteins. The combination of B vitamins is used to influence a number of important processes and functions in the body and, mainly, inflammatory and degenerative diseases of the nerves and the musculoskeletal system. Indications for useIndications for use Combined deficiency of vitamins B1, B6, B12. In the complex treatment of neurological and skin diseases and conditions associated with proven clinical or subclinical deficiency of vitamins B1, B6, B12, such as: non-specific inflammatory and degenerative processes in peripheral nerves – neuritis, polyneuritis (alcoholic, post-infectious, toxic, in diabetes); neuralgia, myalgia, paresthesia; dermatitis, eczema, psoriasis, acne vulgaris, atopic dermatitis. Dosage and administration Neurobeks® is taken orally during or after meals with water. The usual dose is 1-2 tablets 1-3 times a day for 30 days. The doctor determines the individual dose and duration of treatment. Elderly Patients Dose adjustments are generally not required for elderly patients. Impaired renal function In patients with impaired renal function, dose adjustment is not required. Impaired liver function In patients with impaired liver function, dose adjustment is not required. If you have the impression that Neurobex® is too weak or too strong, consult your doctor or pharmacist. If you miss one dose of the drug, take it at the next regular dose without increasing the dose. Use during pregnancy and lactation There are no data on the negative effect of Neurobeks on the fetus and child during pregnancy and lactation. Vitamins penetrate the placental barrier and are excreted from the body with mother’s milk. Due to the lack of sufficient information, the use of the drug is possible only in case of absolute necessity, in recommended doses, as prescribed and under the supervision of a physician, after assessing the benefit / risk ratio, if the benefit outweighs the risk. It should be taken into account that, at high doses, pyridoxine may interfere with prolactin secretion and should be used with caution in nursing mothers. The use of large amounts during pregnancy can lead to pyridoxine dependence syndrome in newborns. Precautions Neurobeks® should be used with extreme caution in patients with severe and acute forms of decompensated heart failure and angina pectoris. During treatment with this drug, you should not drink alcohol, since the ethanol contained in it reduces the amount of vitamin B1 absorbed in the intestines. If the signs of the disease do not begin to disappear, or, on the contrary, the state of health worsens, or adverse events appear, consult a doctor for advice on the further use of the drug! Tablets are not intended for use in children under 6 years of age, as this group of patients may have difficulty swallowing medicines in the form of tablets and capsules. Interaction with other drugs If you are taking any other drugs, be sure to inform your doctor about it, and if you are self-treated, consult a doctor or pharmacist about the possibility of using the drug! Ethyl alcohol dramatically reduces the absorption of vitamin B1. Vitamin B6 affects the metabolism of certain drugs. Co-administration of chloramphenicol, cycloserine, ethionamide, hydralazine, isoniazid, penicillamine, or immunosuppressants with pyridoxine may result in anemia or peripheral neuritis because these agents may act as pyridoxine antagonists or increase renal excretion of pyridoxine. Pyridoxine requirements may be increased in patients receiving these medicinal products. The simultaneous use of estrogens may increase the need for pyridoxine. Co-administration of levodopa with pyridoxine is not recommended because the antiparkinsonian effects of levodopa are reduced by oral pyridoxine at doses in excess of the daily requirement. This problem does not occur when levodopa is combined with a peripheral decarboxylase inhibitor, carbidopa. Serum levels of cyanocobalamin may decrease with oral contraceptives. These interactions are unlikely to be of clinical significance. Antimetabolites and most antibiotics distort the results of analyzes of vitamin B12 in the blood by microbiological methods. Para-aminosalicylic acid, colchicine, biguanides, neomycin, cholestyramine, potassium chloride, methyldopa, and cimetidine may reduce the absorption of vitamin B12. Patients taking chloramphenicol may respond poorly to cyanocobalamin. Contraindications Neurobex® is not used for: allergies to the active or any of the excipients in the composition of the drug; acute thromboembolism (blockage of a vessel by a formed thrombus); erythrocytosis and erythremia (blood diseases caused by an increase in the number of red blood cells). Composition Active substances in one coated tablet: Thiamine nitrate (vitamin B1) 15 mg, Pyridoxine hydrochloride (vitamin B6) 10 mg, Cyanocobalamin (vitamin B12) 0.02 mg. Excipients: lactose monohydrate, wheat starch, talc, magnesium stearate, colloidal silicon dioxide, povidone. Sheath composition: collicoate protect (copolymer of polyvinyl alcohol and polyethylene glycol, polyvinyl alcohol, silicon dioxide), titanium dioxide, talc, cochineal red varnish E124. Information about excipients This medicinal product contains lactose as an excipient and should not be used in patients with lactase deficiency, galactose intolerance or glucose-galactose malabsorption syndrome. Due to the presence of wheat starch in the preparation, it should not be taken by patients with an allergy to wheat (other than celiac disease). The medicine is suitable for patients with celiac disease (gluten enteropathy). Dye E124, which is part of the drug, can cause allergic reactions. Overdose Symptoms: In case of overdose, the symptoms of side effects of the drug increase. Perhaps the appearance of nervous excitement, tachycardia, pain in the heart. Treatment: Treatment includes gastric lavage, the introduction of activated charcoal, the use of symptomatic agents. Isoniazid is an antidote for vitamin B6. Side effects Neurobeks® is generally well tolerated. In rare cases, increased sweating, tachycardia, itching, urticaria are possible. In isolated cases, allergic reactions may occur: rash, suffocation and anaphylactic shock. Severe sensory neuropathy has been described in patients taking high doses of pyridoxine (2 g to 6 g daily) for 2 to 40 months. Sensory peripheral neuropathy is also possible with prolonged use of daily doses of 200 mg or less. If the listed adverse reactions occur, as well as a reaction not indicated in the instructions, you should consult a doctor. Storage conditionsAt temperature not higher than 25°C. Keep out of the reach of children! Buy Neurobex pills p/o in jars No. 90 No. 1 Price for Neurobex pills p / o in jars No. 90 No. 1