Moxioftan eye drops 5mg/ml in a bottle 5ml №1

Name:
Moxioftan. Composition Per 1 ml Active substance: Moxifloxacin hydrochloride monohydrate 5.45 mg in terms of moxifloxacin 5.00 mg Excipients: Sodium chloride 4.40 mg Boric acid 8.00 mg Sodium hydroxide 0.378 mg Purified water up to 1.00 ml
Description:
Clear solution greenish-yellow color. Pharmacotherapeutic group Means used in ophthalmology. Antimicrobial agents. Fluoroquinolones. ATC code: S01AE07. Pharmacological properties Moxifloxacin, a fourth generation fluoroquinolone, inhibits DNA gyrase and topoisomerase IV, which are necessary for replication, repair and recombination of bacterial DNA. It is recommended to take into account official guidelines regarding the proper use of antimicrobial agents. Method of application and dosage For topical use in ophthalmology only. Not for injection. It is not allowed to administer the drug under the conjunctiva or directly into the anterior chamber of the eye. Dosage Adults, including the elderly (over 65 years old) 1 drop in the affected eye (s) 3 times a day. Improvement usually occurs within 5 days. Treatment should also be continued for the next 2-3 days. If there is no improvement within 5 days, the diagnosis and/or treatment should be reassessed. The duration of treatment depends on the severity of the condition, as well as the clinical and bacteriological course of the disease. Children There is no need to adjust the dose of the drug. Patients with impaired liver and kidney function No dose adjustment is necessary. Method of application To prevent microbial contamination of the dropper and solution, care must be taken not to touch the dropper to the eyelid, areas around the eyes and other surfaces. To prevent the absorption of drops through the nasal mucosa, especially in newborns or children, it is necessary to close the lacrimal-nasal canals for 2-3 minutes after applying the drops. When prescribing several ophthalmic drugs, the interval between their use should be at least 5 minutes. Eye ointments should be applied last. Wash your hands thoroughly before instillation. Tilt your head back. Pull your lower eyelid down and look up. Drop 1 drop into the space between the eyelid and the eyeball by pressing on the bottom of the vial. Do not touch the tip of the bottle to the eyelids, eyelashes and do not touch it with your hands. Close your eye and blot it with a dry cotton swab. Without opening your eyes, lightly press its inner corner for 3-5 minutes. This will increase the effectiveness of the drops. Contraindications Hypersensitivity to the active substance, other quinolones or any of the excipients (see Composition section). The most common adverse effects from the use of the drug are eye irritation and eye pain, observed in 1-2% of cases. Undesirable effects were mild in 96% of patients in whom they appeared, treatment was discontinued in only 1 patient. Adverse reactions are listed below, taking into account the system organ class (SOC) and the frequency of their development. The frequency of development is defined as follows: Very often (≥ 1/10) Often (≥ 1/100 – < 1/10) Infrequently (≥ 1/1,000 - < 1/100) Rarely (≥ 1/10,000 - < 1/10) 1,000) Very rare (<1/10,000) Frequency not known (cannot be estimated from the available data). SS Frequency Adverse reactions Side effects Rare Decreased hemoglobin of the hematopoietic and lymphatic systems Side effects Unknown Hypersensitivity of the immune system Side effects Uncommon Nervous system headache Rare Paresthesia Unknown bleeding, eye flushing, eye itching, eyelid edema, eye discomfort Rare Corneal epithelial injury, corneal injury, conjunctivitis, blepharitis, eye oedema, conjunctival oedema, blurred vision, decreased visual acuity, asthenopia, eyelid erythema Unknown Endophthalmitis, ulcerative keratitis, corneal erosion, corneal thinning, increased intraocular pressure, corneal clouding, corneal infiltrate, corneal deposits, eye allergy, keratitis, corneal edema, photophobia, increased lacrimation, secretion from the eyes, foreign body sensation in the eye Cardiac disorders Unknown Palpitations Respiratory disorders Rare Nasal, pharyngo-laryngeal pain, system, chest organs Foreign body sensation in the throat and mediastinum Unknown Dyspnea Gastrointestinal disorders Uncommon Taste disorders of the intestinal tract Rare Vomiting Unknown Nausea Disorders from the liver and rarely Increased levels of alanine aminotransferase (ALT), biliary tract gamma glutamyl transferase (GGT) Skin disorders and Unknown Redness, rash, itching, urticaria of the subcutaneous tissues