Name:
Magnesium-Diasporal 300 gran. in pack. 5.0g per pack №50
Description:
Yellow granules. When 5 g of granules are dissolved in 75 ml of water, a solution with a characteristic odor is formed. Main active ingredient Magnesium citrate Release form Granules. Dosage 300 grn.d/app. in pack. 5.0 g Pharmacological action Mineral additives. Magnesium based products. ATX code: A12CC04. Indications for use Treatment of magnesium deficiency. If you need more information about your condition, ask your doctor for advice. Dosage and Administration Adults (> 18 years): 1 sachet per day (295.7 mg magnesium). How to use: Dissolve the contents of one sachet in half a glass of fruit juice, tea or water and drink half an hour before meals. Children and Adolescents: The safety and efficacy of Magnesium Diasporal® 300 in children and adolescents have not been established. Application in geriatric practice Dosages in elderly patients are determined by the degree of impairment of their liver and / or kidney function. Use in persons with impaired renal function In patients with moderate renal impairment, it is recommended to use with caution. In severe renal dysfunction (creatinine clearance < 30 ml / min), the use of the drug is contraindicated. Use in persons with impaired liver function: Due to the lack of sufficient data, there are no dosage recommendations. Duration of treatment: The duration of treatment depends on the degree of magnesium deficiency and is determined by the doctor individually. If the next dose of the drug was missed, do not take a double dose of Magnesium-Diasporal® 300, trying to compensate for the missed dose. Application during pregnancy and lactation Magnesium-Diasporal® 300 can be used during pregnancy and breastfeeding only on the advice of a doctor. There is no evidence of risk for developmental defects. However, documented experience with women in the early stages of pregnancy is very limited. Precautions The drug contains sucrose, so patients with rare hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency should not take it. Prolonged use (2 weeks or more) can damage teeth. 1 sachet of the drug contains 145.0 mg of sodium bicarbonate or 39.79 mg (1.73 mmol) of sodium, which should be taken into account in patients on a sodium-restricted diet. Use in persons with impaired liver and / or kidney function With caution in moderate renal insufficiency (danger of developing hypermagnesemia). In patients with severe renal impairment (creatinine clearance < 30 ml / min), the use of the drug is contraindicated. Information on the use of the drug in violation of liver function is not enough, so there are no recommendations related to the peculiarities of use in patients with liver failure. Application in geriatric practice Dosages in elderly patients are determined by the degree of impairment of their liver and / or kidney function. Interaction with other drugs Magnesium salts may increase the activity of neuromuscular blockers (eg, pancuronium bromide, succinylcholine halide). Some drugs accelerate the excretion or inhibit the absorption of magnesium and can thus cause magnesium deficiency. Therefore, dosage adjustment of magnesium may be required when the drug is used concomitantly with the following agents: diuretics (such as thiazides and furosemide), proton pump inhibitors (such as omeprazole and pantoprazole), platinum derivatives (particularly cisplatin), aminoglycoside antibiotics, rapamycin, amphotericin B, foscarnet, cyclosporine A, EGF receptor antagonists (eg, cetuximab and erlotinib), and pentamidine. Ions of magnesium, iron, fluoride and tetracycline mutually influence each other's absorption, therefore it is necessary to observe at least 3 hours interval between taking Magnesium-Diasporal® 300 and preparations containing iron, fluorine and tetracycline. Magnesium weakens the effect of indirect anticoagulants. ContraindicationsHypersensitivity to the active substance or auxiliary components of the drug listed in the "Composition" section. Severe renal failure (glomerular filtration rate < 30 ml / min.). Cardiac arrhythmia leading to bradycardia. Composition One sachet (5.0 g) contains: Active ingredient: Magnesium citrate 1830 mg Equivalent to magnesium content 295.7 mg Excipients: sucrose, anhydrous citric acid, sodium bicarbonate, riboflavin (E101), orange juice flavor. Overdose In the case of healthy kidney function, magnesium toxicity due to an overdose of oral magnesium is not expected. Only in the case of severe renal insufficiency can accumulation of magnesium be observed in combination with manifestations of intoxication. Symptoms: With oral therapy with magnesium preparations, an overdose usually does not lead to toxic reactions, if kidney function is not impaired. Diarrhea may occur, which disappears after a decrease in the daily dose. Fatigue can be a sign of high levels of magnesium in the blood. Only in the case of severe renal failure with anuria, both oral and parenteral therapy with magnesium preparations can lead to its accumulation and symptoms of intoxication. Depending on the concentration of Mg in plasma (in mmol / l), the following symptoms are observed: 1.5 - lowering blood pressure, nausea, vomiting; 2.5 - depression of the central nervous system; 3.5 - inhibition of reflexes, changes in the ECG; 5.0 - beginning of respiratory depression; 5.5 - coma; 7.0 - cardiac arrest and respiratory paralysis, anuric syndrome. Treatment: Intravenous administration of calcium (10-20 ml of 10% calcium gluconate solution); the use of loop diuretics, which increase the excretion of magnesium in the urine; symptomatic and supportive therapy. In renal failure: hemodialysis, peritoneal dialysis. Side effectEvaluation of adverse events is based on the following indicators of the frequency of occurrence: Very often (? 1/10); often (from? 1/100 to <1/10); infrequently (from? 1/1000 to <1/100); rarely (from? 1/10000 to <1/1000); very rarely (<1/10000); frequency not known (not enough data to estimate). Gastrointestinal disorders Uncommon: soft stools or diarrhea at the beginning of treatment (harmless and transient). General disorders Very rare: fatigue when used for a long time. It is necessary to temporarily suspend treatment and continue with a reduced dosage after improvement and / or disappearance of symptoms. If the listed adverse reactions occur, as well as a reaction not indicated in the instructions for use, it is necessary to inform the doctor. Storage conditions Keep out of the reach of children, at a temperature of 15 C to 25 C. Buy Magnesium-Diasporal 300 granules for oral solution in 5.0g bags in bags 5.0g No. 50Instruction for use for Magnesium-Diasporal 300 granules for oral solution in bags 5.0g No. 50
Magnesium-Diasporal 300 granules for solution for oral administration in bags 5.0g №50
$57.00
INN | MAGNESIUM CITRATE |
---|---|
The code | 96 993 |
Barcode | 4 260 124 360 183 |
Active substance | Magnesium citrate |
Manufacturer | Protina Pharm. Gesel. mbH, Germany |
Importer | IOOO Interfarmaks 223028 Minsk region, Minsk district, Zhdanovichsky s / s, ag. Zhdanovichi, st. Star, 19a-5, room. 5-2 |
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