Ketotifen tablets 1mg №10×3

Name Ketotifen tablets 1mg in a cell. pack No. 10×3 The main active ingredient Ketotifen Release form Tablets Dosage 1 mg Pharmacological action Pharmacological action – membrane-stabilizing, anti-allergic, antihistamine, anti-asthma. Prevents the development of bronchospasm (does not have a bronchodilatory effect). It has a depressant effect on the central nervous system. Indications for use Prevention and treatment of multisystem allergic diseases: chronic idiopathic urticaria (for example, cold urticaria); allergic rhinitis with or without concomitant bronchial asthma; allergic conjunctivitis; atopic dermatitis. The use of Ketotifen does not replace treatment with corticosteroids (inhaled or systemic), if corticosteroids are indicated for the treatment of bronchial asthma. Dosage and administration The drug is taken orally with meals. Adults are prescribed 1 mg (1 tablet) twice a day (morning and evening). In patients prone to sedation, a slow increase in dose during the first week is recommended. It is recommended to start taking 1 tablet once a day in the evening and increase the dose over 5 days to the full daily dose. If necessary, the daily dose can be increased to 4 mg (4 tablets) and divided into two doses. When using higher doses, a faster onset of effect can be expected. Children over the age of 3 years are prescribed 1 mg (1 tablet) twice a day (morning and evening). Given that the study of pharmacokinetics has established a high rate of metabolism of ketotifen, children may need to prescribe higher doses of the drug in terms of kilograms of body weight to achieve the optimal effect. At the same time, the tolerance of such doses remains good. Simultaneous use of bronchodilators. When taking ketotifen, the frequency of taking bronchodilators may be reduced. Use in the elderly. When prescribing ketotifen to the elderly, dose adjustment is not required. Duration of therapy Several weeks are required to achieve the full therapeutic effect of ketotifen. If within a few weeks the patient does not have a reaction to taking ketotifen, its further use to achieve a lasting effect should continue for at least 2-3 months. Cancellation of ketotifen should be carried out gradually over 2-4 weeks, while exacerbation of the symptoms of an allergic disease is possible. If the pill was missed, it should be taken as soon as possible, and the next one at the scheduled time. Do not take a double dose to make up for a missed one. Use during pregnancy and lactation Although there is no evidence of a teratogenic effect, taking ketotifen during pregnancy is not recommended. Ketotifen is excreted in breast milk, so mothers receiving ketotifen should not breastfeed their baby. Influence on the ability to drive vehicles and other potentially dangerous mechanisms Ketotifen may weaken the patient’s response. During the period of treatment, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions. Precautions It is undesirable to abruptly cancel the previous treatment with beta-adrenergic stimulants, glucocorticosteroids, adrenocorticotropic hormone preparations in patients with bronchial asthma and bronchospastic syndrome after joining ketotifen therapy, cancellation is carried out for at least 2 weeks, gradually reducing the dose. Treatment is stopped gradually, within 2-4 weeks (possible recurrence of asthmatic symptoms). For persons sensitive to sedation, in the first 2 weeks, the drug is prescribed in small doses. Not intended for the relief of an attack of bronchial asthma. In patients simultaneously receiving oral hypoglycemic drugs, the number of platelets in the peripheral blood should be monitored. During treatment with ketotifen, seizures are extremely rare. Since ketotifen can lower the seizure threshold, it is contraindicated in patients with epilepsy (see section “Contraindications”). In patients with chronic idiopathic urticaria, no studies have been conducted on the effectiveness and long-term (over 4 weeks) administration of ketotifen. In the case of intercurrent infections, ketotifen therapy should be supplemented with antibacterial treatment. Ketotifen tablets contain lactose. Patients with rare hereditary problems of galactose intolerance, severe lactase deficiency or glucose-galactose malabsorption should not take ketotifen. Interaction with other drugs Enhances the effect of sedatives, hypnotics, antihistamines, ethanol. When taking ketotifen and oral hypoglycemic drugs together, it is necessary to control the platelet count due to an increased likelihood of developing thrombocytopenia. Contraindications Hypersensitivity to any of the components of the drug, pregnancy, lactation (if necessary, the use of the drug should stop breastfeeding), children under 3 years of age, epilepsy and history of convulsions. With caution: liver failure. Composition Each tablet contains: active substance – ketotifen (in the form of ketotifen fumarate) – 1 mg; excipients – microcrystalline cellulose, croscarmellose sodium, magnesium stearate, anhydrous colloidal silicon dioxide, lactose monohydrate. Overdose Symptoms: drowsiness, nystagmus, confusion, disorientation, bradycardia or tachycardia, lowering blood pressure, shortness of breath, cyanosis, convulsions, irritability (especially in children), coma may develop. Treatment: induction of vomiting, gastric lavage (if a little time has passed since ingestion), the appointment of activated charcoal, saline laxatives; symptomatic treatment, with the development of a convulsive syndrome – short-acting barbiturates and benzodiazepines. Dialysis is ineffective. Side effects The frequency of side effects is given in the following gradation: very often (? 1/10); often (? 1/100, < 1/10); infrequently (? 1/1000, < 1/100); rarely (? 1/10000, < 1/1000); very rarely (< 1/10000); unknown (according to the available data, it is not possible to determine the frequency of occurrence). From the side of the central nervous system: infrequently - dizziness, slow reaction rate (disappear after a few days of therapy), sedation, feeling of fatigue; rarely - anxiety, sleep disturbances, nervousness (especially in children); unknown - convulsions, drowsiness, headache. From the immune system: very rarely - erythema multiforme, Stevens-Johnson syndrome, severe skin reactions. From the skin side: unknown - rash, urticaria. From the hemopoietic system: very rarely - thrombocytopenia. From the digestive system: infrequently - increased appetite, dryness of the oral mucosa; rarely - dyspeptic phenomena; unknown - nausea, vomiting, constipation, diarrhea. On the part of the liver: very rarely - hepatitis, increased levels of liver enzymes. From the side of metabolism: rarely - weight gain. From the urinary system: infrequently - dysuria, cystitis. In the event of the above adverse reactions or adverse reactions not listed in this leaflet, you should consult a doctor. Storage conditions In a place protected from moisture and light at a temperature not exceeding 25 ° C. Keep out of the reach of children. Buy Ketotifen tablets 1mg No. 10x3 Price for Ketotifen tablets 1mg No. 10x3