Name:
Iodinol solution dnar. note in 100 ml vial in pack No. 1
Description:
Dark blue liquid with a characteristic odor, foaming when shaken. Traces of foaming are allowed on the unfilled part of the vial. Composition One vial contains: active ingredient – iodine – 100 mg; excipients – potassium iodide, polyvinyl alcohol, purified water. Pharmacotherapeutic group Antiseptic and disinfectants. ATX code – D08AG03. Pharmacological action Pharmacodynamics Iodinol (iodine polyvinyl alcohol, iodine polyvinyl alcohol) is a product of the addition of molecular (crystalline) iodine to polyvinyl alcohol. Iodinol has low toxicity. Has antiseptic properties. When applied to large skin surfaces, iodine has a resorptive effect: it actively affects metabolism, enhances dissimilation processes, participates in the synthesis of thyroxine, and has a proteolytic effect; polyvinyl alcohol – a high-molecular compound, the content of which in iodinol slows down the release of iodine and lengthens its interaction with body tissues; also reduces the irritating effect of iodine on tissues. Iodine has a bactericidal effect on both gram-positive and gram-negative flora, as well as pathogenic fungi and yeasts, most actively on streptococcal flora and E. coli. Staphylococci are more resistant to the action of iodinol, however, with prolonged use in 80% of cases, their elimination is observed. Pseudomonas aeruginosa is resistant to the use of Iodinol. Pharmacokinetics Upon contact with skin or mucous membranes, 30% turns into iodides, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs and is selectively absorbed by the thyroid gland. It is excreted mainly by the kidneys, intestines, sweat and mammary glands. Indications for use Chronic tonsillitis, chronic purulent otitis media, chronic atrophic rhinitis (ozena), purulent wounds, trophic and varicose skin ulcers, thermal and chemical burns of I-II degree. Contraindications Hypersensitivity to the components of the drug, thyrotoxicosis, pregnancy and lactation, thyroid diseases (colloidal nodular goiter, endemic goiter and Hashimoto’s thyroiditis), Dühring’s dermatitis herpetiformis, simultaneous therapy with radioactive iodine, children under 6 years of age (no experience of use). Precautions Use with caution in patients under the age of 18 years. Avoid getting the drug in the eyes. If this occurs, the eyes should be flushed with plenty of water or 1% sodium thiosulfate solution. In persons with renal and hepatic insufficiency, as well as in persons over the age of 70 years, Iodinol should be used with extreme caution under the control of thyroid function (1 time in 2 weeks). Influence on laboratory parameters During treatment with Iodinol, it is possible to obtain false results in determining the level of thyroid hormones and protein-bound iodine in blood plasma. Influence on the ability to drive vehicles and control mechanisms Currently, there is no evidence that Iodinol affects the ability to drive vehicles and control mechanisms. Pregnancy and lactation Pregnancy The amount of iodine that can be absorbed by the use of this drug is a priori low. However, iodine-based preparations should not be given during pregnancy, especially in the third trimester, due to the risk of fetal hypothyroidism and neonatal goiter. Therefore, as a precautionary measure, the use of this drug during pregnancy should be avoided. Lactation Iodine is excreted in mother’s milk, so the use of the drug during breastfeeding should be avoided. Dosage and administration In chronic tonsillitis, the lacunae of the tonsils and the supratonsillar space are washed. Only 4-5 washes with an interval of 2-3 days. Single dose 50 ml. With purulent otitis: daily instillation of 5-8 drops of Iodinol (in case of mesotympanitis) or washing of the attic (with epitympanitis). The course of treatment is 2-4 weeks. In the treatment of atrophic rhinitis (ozena), after preliminary softening and removal of crusts, the nasal cavity and pharynx are irrigated with Iodinol 2-3 times a week for 2-3 months. For trophic and varicose ulcers, the skin is pre-washed with warm water and soap, the area around the ulcer is smeared with zinc ointment. A bandage of three layers of gauze moistened with Iodinol is applied to the surface of the ulcer. Dressings are carried out 1-2 times a day (as the dressing becomes discolored), while the gauze lying on the surface of the ulcer is not removed, but re-impregnated with Iodinol. 4-7 days after the general or local bath, the indicated treatment is continued. For purulent wounds and infected burns, a loose gauze dressing is applied, impregnated with a drug and replaced periodically, as needed. Wound cavities are washed with Iodinol, after which it is introduced into the cavity on a swab. OverdoseSymptoms for external use: iodism phenomena – skin rashes, rhinitis, lacrimation, hypersalivation, rhinorrhea, bronchorrhea, swelling of the mucous membranes. Treatment: drug withdrawal, symptomatic therapy. Symptoms of accidental or deliberate use of Iodinol inside: iodism phenomena – a metallic taste in the mouth, increased salivation, increased sweating, burning or pain in the throat and mouth, eye irritation and swelling of the eyelids, nasopharynx, larynx, difficulty breathing (pulmonary edema), skin reactions, gastrointestinal disorders (nausea, vomiting, intestinal cramps and diarrhea). Tachycardia, metabolic acidosis, hypernatremia, and renal failure may develop. Treatment: gastric lavage first with 1% sodium thiosulfate solution, then with water; symptomatic therapy. Interaction with other drugs The drug is not compatible with disinfectants containing mercury compounds, it is pharmaceutically incompatible with essential oils, ammonia solutions, antiseptics from the group of alkalis and oxidizers. Changes the effectiveness of drugs affecting thyroid function. Iodinol can be combined with physiotherapy, and, if necessary, with antibiotics. Absorption of iodine from Iodinol may affect thyroid function. Alkaline or acidic environment, the presence of fat, pus, blood weaken the antiseptic activity. Side effect Allergic reactions (skin itch). Individuals with idiosyncrasy to iodine may experience iodism phenomena in the form of skin rashes or rhinitis, itching, swelling and irritation of the mucous membranes (lacrimation, hypersalivation, rhinorrhea, bronchorrhea), which does not require any special measures or discontinuation of treatment. From the thyroid gland: goiter, hypothyroidism or hyperthyroidism. Metabolic acidosis, hypernatremia and impaired renal function (when applied to a large area of mucous membranes or in persons with extensive burns). Upakovka100 ml in glass bottles. Each vial, together with the leaflet, is placed in a cardboard box (packaging No. 1). Storage conditions In a place protected from light, at a temperature not exceeding 25 ° C. Do not freeze. Keep out of the reach of children. Shelf life 3 years. Do not use the medicine after the expiration date. Terms of dispensing from pharmaciesWithout a prescription. Buy Iodinol solution for external use 100ml №1 Price for Iodinol solution for external use 100ml №1Instruction for use for Iodinol solution for external use 100ml №1
INN | IODINE + POTASSIUM IODIDE |
---|---|
The code | 71 712 |
Barcode | 4 810 201 004 648 |
Dosage | 100ml |
Active substance | Iodine, potassium iodine, polyvinyl alcohol |
Manufacturer | Borisovsky ZMP, Belarus |
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