Iodbalance tablets 100mcg №25×4

Name:
Iodbalance tabl 100mkg in a blister. in pack. No. 25×4 Main active ingredient Potassium iodide
Description:
Iodine balance, tablets 100 mcg: from almost white to yellowish-gray round tablets, flat on both sides, with beveled edges. On both sides of the tablet there is a dividing line, on one side of the tablet there is an engraving “EM 33”. 25 tablets in PVC / aluminum blister. 4 blisters with instructions for use are placed in a cardboard box. Dosage 100mkg Pharmacological actionPharmacodynamicsIodine is one of the vital trace elements. Without iodine, the normal functioning of the thyroid gland is impossible, since it is an integral part of thyroxine and triiodothyronine. Thyroid hormones are involved in the development of all organs and systems, in the regulation of metabolic processes in the body: protein, fat, carbohydrate and energy, they also regulate the activity of the brain, nervous and cardiovascular systems, sex and mammary glands, the growth and development of the child, the formation of his intellectual abilities. Iodine deficiency is especially dangerous for children, adolescents, pregnant and lactating women. Iodbalance®, being a source of iodine, compensates for its deficiency in the body, prevents the development of iodine deficiency diseases, prevents the development of goiter associated with a lack of iodine in food; normalizes the size of the thyroid gland in newborns, children, adolescents and adults. Pharmacokinetics When taken orally, the drug is almost completely absorbed in the small intestine. The average volume of distribution for healthy people is approximately 23 liters (38% of body weight). The plasma concentration of iodine is normally from 0.001 to 0.005 μg / ml. It accumulates in the thyroid gland, salivary glands, mammary glands and stomach tissues. The concentration in saliva, gastric juice and breast milk is approximately 30 times higher than in blood plasma. Excreted in the urine, the concentration of iodine in the urine relative to creatinine (mcg / g) is an indicator of its intake into the body. Indications for use – prevention of iodine deficiency diseases, incl. endemic goiter (especially in pregnant and lactating women); – prevention of goiter recurrence after its surgical removal, as well as at the end of goiter treatment with thyroid hormone preparations; – treatment of diffuse euthyroid goiter in newborns, children, adolescents and young adult patients. Application during pregnancy and lactation During pregnancy and breastfeeding, the need for iodine increases, so it is especially important to use Iodbalance in sufficient doses to ensure adequate intake of iodine in the body (the recommended intake of iodine is 250 mcg per day). The drug crosses the placenta and is excreted in breast milk. If a nursing woman takes Iodbalance®, additional administration of the drug to infants who are breastfeeding is not required. The use of the drug during pregnancy and during breastfeeding is possible only in recommended doses. When carrying out therapy, it is necessary to take into account the amount of iodine supplied with food. Precautions Iodine deficiency increases, and its excess reduces the response to thyrostatic therapy in patients with hyperthyroidism. Therefore, in the period preceding this therapy, and during the treatment of hyperthyroidism, it is necessary, if possible, to avoid prescribing any iodine preparations. The use of the drug should be avoided before the diagnosis and during therapy with radioactive iodine, the presence or suspicion of thyroid cancer. Do not use the drug in hypothyroidism, except in cases where hypothyroidism is caused by iodine deficiency. The drug crosses the placenta well and can cause the development of hypothyroidism and goiter in the fetus if potassium iodide is taken in large doses. The drug passes into breast milk. Therefore, the use of potassium iodide preparations during pregnancy and lactation is possible only in recommended doses. When using the drug, it is necessary to take into account the amount of iodine coming from other sources (iodized salt, food enriched with iodine, vitamin and mineral complexes, etc.). If a nursing woman takes Iodbalance, additional use of the drug for breastfeeding infants is not required. It should be borne in mind that during drug therapy in patients with renal insufficiency, hyperkalemia may develop. Iodbalance does not affect the ability to drive vehicles and control mechanisms. Interaction with other drugs Thyrostatic drugs inhibit the conversion of iodine to the form associated with organic substances inside the thyroid gland and therefore can cause goiter. Substances taken up by the thyroid through the same “trapping” mechanism as iodide can inhibit thyroid uptake of iodine through a competitive mechanism (eg, perchlorate, which also inhibits iodide recycling within the thyroid). Inhibition is also possible from drugs that are not themselves absorbed, such as thiocyanate, at concentrations greater than 5 mg/dl. The intake of high doses of iodine and the simultaneous administration of potassium-sparing diuretics can lead to the development of hyperkalemia. Simultaneous administration of iodine therapy in high doses with lithium preparations contributes to the development of goiter and hypothyroidism. The absorption of iodine by the thyroid gland and its metabolism are stimulated by thyroid-stimulating hormone. Quinidine: with simultaneous use, there is an increase in the effect of quinidine on the heart due to an increase in the concentration of potassium in the blood plasma. Vegetable alkaloids and salts of heavy metals: simultaneous use may lead to the formation of an insoluble precipitate and complicate the absorption of iodine. Contraindications Manifest (or overt) hyperthyroidism; latent (or latent) hyperthyroidism (when using doses exceeding 150 mcg / day); Dühring’s herpetiform dermatitis; solitary toxic adenomas of the thyroid gland and functional autonomy of the thyroid gland (focal and diffuse), nodular toxic goiter (for with the exception of preoperative therapy for the purpose of blockade of the thyroid gland); hypersensitivity to the active substance or auxiliary components of the drug; pulmonary tuberculosis; hemorrhagic diathesis. avoid during therapy with radioactive iodine, the presence or suspicion of thyroid cancer. Since the drug contains lactose monohydrate, it is not recommended to prescribe it to patients with rare hereditary diseases associated with galactose intolerance, lactase or glucose-galac deficiency tonic malabsorption. Composition Each tablet contains: Active ingredient: potassium iodide 130.8 mcg (corresponds to 100 mcg of iodine). Excipients: magnesium stearate (E470), microcrystalline cellulose (E460), colloidal silicon dioxide (E551), corn starch, cellulose powder, lactose monohydrate. Method of application and doses Prevention of the development of iodine deficiency diseases, incl. endemic goiter: Newborns and children up to 5 years of age inclusive: 50 mcg of iodine per day (1/2 tablet of Iodine balance 100 mcg). Children 6-12 years old: 100 micrograms of iodine per day (1 tablet of Iodine Balance 100 micrograms). Children over 12 years of age and adults: 150 mcg of iodine per day (1/2 tablet of Iodbalance 100 mcg). During pregnancy and lactation: 200 mcg of iodine per day (2 tablets of Iodbalance 100 mcg). Prevention of goiter recurrence after its surgical removal or at the end of a course of treatment with thyroid hormone preparations: 100-200 mcg of iodine daily (1-2 tablets of Iodbalance 100 mcg). Treatment of euthyroid goiter: Newborns, children, adolescents: 100-200 micrograms of iodine per day (1-2 tablets of Iodine Balance 100 micrograms). Young adult patients (under 40): as directed by the physician. The daily dose of the drug should be taken in one dose, after meals, drinking plenty of fluids. When prescribing the drug to newborns and children under 3 years old, it is recommended to dissolve the tablet in a small amount (1 tablespoon) of boiled water at room temperature. The use of the drug for prophylactic purposes is carried out for, as a rule, several months or years, and often throughout life. For the treatment of goiter in newborns, in most cases, 2-4 weeks are enough; in children, adolescents and adults, it usually takes 6-12 months or more. The duration of treatment is determined by the doctor. When determining the dose of the drug, it is necessary to take into account national guidelines for the proper use of the drug for the prevention and treatment of diseases caused by iodine deficiency. If you forget to take Yodbalance on time, continue taking the drug as usual. Do not take a double dose to make up for a single missed dose. Overdose Symptoms of intoxication: Brown staining of the mucous membranes, vomiting, abdominal pain and diarrhea. This can lead to dehydration and shock. In rare cases, stenosis of the esophagus. In the case of taking large amounts of iodine, deaths were recorded (from 30 to 250 ml of iodine, which corresponds to 0.75-6.25 g E). Chronic overdose can lead to the phenomenon of “iodism”: a metallic taste in the mouth, swelling and inflammation of the mucous membranes (rhinitis, conjunctivitis, gastroenteritis, bronchitis); bullous or tuberous iododerma, exfoliative dermatitis and angioedema. Rare cases of fever and acne, as well as swelling of the salivary glands, have been reported. Treatment of acute intoxication: Gastric lavage, symptomatic treatment of water and electrolyte disorders and shock. Treatment of chronic intoxication: Cancellation of iodine preparations. Hypothyroidism caused by iodine intake: it is recommended to stop the use of the drug and start replacement therapy with thyroid hormones. Hyperthyroidism caused by iodine intake: In this case, we cannot talk about an overdose as such, since hyperthyroidism can also be caused by an amount of iodine that is normal in other countries. Treatment according to the form of the course: with a mild form, treatment is usually not required; with pronounced forms, thyreostatic therapy is indicated (the effect, which, however, occurs somewhat later). In the most severe cases (thyrotoxic crisis): intensive care, plasmapheresis or thyroidectomy. Side effects In the prophylactic use of Iodbalance, as well as in therapeutic use in newborns, children and adolescents, as a rule, no adverse reactions are observed. From the immune system: with an unknown frequency – hypersensitivity reactions (rhinitis, exfoliative dermatitis, rash, Quincke’s edema, bullous or tuberous iododerma, fever, acne, swelling of the salivary glands). Patients with a predisposition to autoimmune thyroiditis may develop antibodies to TPO. On the part of the blood: very rarely – eosinophilia. From the side of the cardiovascular system: in isolated cases – tachycardia, tremor. From the side of the central nervous system: in isolated cases – irritability, sleep disturbance, increased sweating. From the gastrointestinal tract: discomfort in the epigastric region, in isolated cases – diarrhea (in patients over 40 years of age). On the part of the endocrine system: With long-term administration of high doses of the drug (more than 300 mcg per day), iodine-induced hyperthyroidism may develop (especially in elderly patients, in the presence of nodular goiter or toxic adenoma). When treating with high doses of iodine (more than 1,000 mcg per day), in some cases, iodine-induced goiter and hypothyroidism may develop. If the listed adverse reactions occur, as well as a reaction not indicated in the instructions for use, you should consult a doctor. Storage conditions At a temperature not higher than 30 °C. Keep out of the reach of children. Buy Iodbalance tablets 100mcg No. 25×4