Name:
Heparin, ointment for external use.
Description:
Ointment of white color with a yellowish tinge. The main active ingredient is sodium heparin + benzocaine + benzyl nicotinate. Release form Ointment. Pharmacological action Heparin ointment, when applied to the skin, has an anti-inflammatory effect, prevents the formation of blood clots and has a local anesthetic effect. Indications for use Thrombophlebitis of superficial veins, post-injection and post-infusion phlebitis, inflammation of external hemorrhoids. Method of administration and doses Thrombophlebitis of superficial veins, post-injection and post-infusion phlebitis. The ointment is applied in a thin layer (0.5-1 g per area with a diameter of 3-5 cm) on the affected area and gently rub the ointment into the skin. Inflammation of external hemorrhoids. The ointment is applied to a calico or linen pad, which is applied directly to the hemorrhoids and fixed with a bandage. For the same purpose, you can use a swab soaked in heparin ointment, which is inserted into the anus. For children, the drug is applied in a thin layer to the affected area of the skin and rubbed with light movements. A single dose for children depends on the area of the lesion and can be 0.5 – 3 cm of the ointment column. The ointment is used 2-3 times a day daily until the disappearance of inflammation, no more than 10 days. Use during pregnancy and lactation The safety of the drug during pregnancy and lactation has not been established. Heparin does not cross the placental barrier and is not excreted in breast milk. There is no information about the ingress of other components of the drug into breast milk. Heparin ointment is used during pregnancy and lactation (breastfeeding) only if the intended benefit to the mother outweighs the potential risk to the fetus or child. Precautions With prolonged use of heparin ointment over large areas and the simultaneous use of oral drugs that affect the blood coagulation system and / or hematopoiesis, clotting time and prothrombin time should be monitored. If a long course of treatment is necessary and with extensive lesions in pregnant women and in women over the age of 65, a similar control is recommended. It should not be applied to open wounds, in the presence of purulent processes. The use of the ointment is not recommended for deep venous thrombosis. Patients with a history of thromboembolic complications should be prescribed drugs Heparin, an ointment for external use, with caution, due to the possibility of its systemic action. For the purpose of differential diagnosis of type II heparin-induced thrombocytopenia, it is recommended to determine the number of platelets in the blood. Methyl parahydroxybenzoate and propyl parahydroxybenzoate may cause delayed allergic reactions. Interaction with other drugs The anticoagulant effect of heparin is enhanced with the simultaneous use of anticoagulants, antiplatelet agents and non-steroidal anti-inflammatory drugs. Ergot alkaloids, thyroxine, tetracycline, antihistamines and nicotine reduce the effect of heparin. The ointment is not prescribed topically simultaneously with non-steroidal anti-inflammatory drugs (NSAIDs), tetracyclines, H1-histamine receptor blockers. Contraindications Hypersensitivity to the components of the drug; violation of the integrity of the skin of the affected area (open infected wounds, ulcerative necrotic processes in particular); children’s age up to one year. Hypocoagulation, thrombocytopenia. The presence or history of heparin-induced thrombocytopenia type II. Composition Per tube: active substance: heparin (in the form of sodium heparin) – 2500 IU; benzocaine (anesthesin) – 1000.0 mg, benzyl nicotinate – 20.0 mg; excipients: glycerin, emulsifier No. 1, soft paraffin, white, stearic acid, sunflower oil, methyl parahydroxybenzoate, propyl parahydroxybenzoate, purified water. Overdose So far, overdose phenomena have not been described when using heparin ointment. With prolonged use on large surfaces, hemorrhagic complications are possible. Treatment: drug withdrawal. If necessary, use the heparin antagonist protamine sulfate (1% solution). Side effects With prolonged use of the drug, local reactions are possible in the form of skin hyperemia, decreased sensitivity at the site of application, allergic reactions (skin rash, itching). The risk of developing heparin-induced, antibody-mediated thrombocytopenia type II (with a decrease in the number of platelets < 100,000 × 109 or a rapid drop in the number of platelets to < 50% of baseline, with arterial or venous thrombosis or embolism) cannot be excluded when using topical forms heparin. Therefore, when using heparin ointment, the number of platelets in the blood should be additionally monitored in patients with a history of thromboembolic complications. With parenteral heparin in patients without pre-existing hypersensitivity to heparin, a decrease in the number of platelets, as a rule, can occur 6-14 days after the start of treatment. In patients with hypersensitivity to heparin, thrombocytopenia may develop within a few hours. In the event of the above adverse reactions or adverse reactions not listed in these instructions for medical use of the drug, you should consult a doctor. Storage conditions At a temperature not higher than 25 °C. Keep out of the reach of children. Buy Heparin ointment 25g №1 Price for Heparin ointment 25g №1Instruction for use for Heparin ointment 25g №1
Heparin ointment 25g №1
$8.00
SKU: 2682
Category: Treatment and prevention of hemorrhoids and varicose veins
INN | HEPARIN |
---|---|
The code | 2 682 |
Barcode | 4 810 133 000 466 |
Dosage | 25g |
Active substance | Heparin |
Manufacturer | Belmedpreparaty RUE, Belarus |
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