NameGepsil-Pn tabl.p/o 35mg in cell.pack No. 15×8 Main active ingredient Silibinin Release formPills Dosage 35 mg Special instructions During pregnancy and lactation, the drug is used only under the supervision of a doctor. Pharmacological actionMeans for the treatment of liver diseases. Indications for use Symptomatic treatment of chronic toxic liver damage; for maintenance treatment in patients with chronic inflammatory liver disease or cirrhosis. Dosing and Administration Take the tablets whole with a sufficient amount of liquid. Unless otherwise provided, 4 tablets 3 times a day (equivalent to 420 mg of silymarin). Use during pregnancy and lactation During pregnancy and lactation, the drug is used provided that the expected benefit from the treatment is greater than the risk of its use. The ability to influence the reaction rate when driving vehicles or working with other mechanisms Does not affect the ability to drive vehicles and maintain moving mechanical devices. Precautions Taking the drug cannot replace dieting or not taking hepatotoxic substances for liver damage (for example, from alcohol). The medicinal product contains lactose monohydrate as an excipient. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. When using the drug, an estrogen-like effect of silymarin is possible. Therefore, in patients with hormonal disorders (endometriosis, uterine fibroids, carcinoma of the breast, ovaries, uterus, prostate), the drug is prescribed with caution. In these cases, consultation with a specialist is necessary. Interaction with other drugs When combined with silymarin with oral contraceptives and drugs that are used in hormone replacement therapy, it is possible to reduce the effects of the latter. Silymarin inhibits the cytochrome P450 system and may enhance the effects of drugs such as diazepam, alprazolam, ketoconazole, lovastatin, vinblastine. Contraindications The drug is well tolerated. The following side effects can rarely be observed: from the gastrointestinal tract: nausea, dyspepsia, diarrhea; on the part of the skin and subcutaneous fatty tissue: in some cases, skin allergic reactions are possible – itching, rash; on the part of the organ of hearing and balance: it is rarely possible to observe an increase in existing vestibular disorders. Side effects are transient and disappear after discontinuation of the drug. Composition 1 tablet contains: active substance: dry extract from fruits of milk thistle is equivalent to 35 mg of silymarin; excipients: microcrystalline cellulose, sodium starch glycolate (type A), magnesium stearate, povidone, lactose monohydrate; shell (polyvinyl alcohol, macrogol, talc, black iron oxide, red iron oxide, yellow iron oxide, titanium dioxide). Dosage form: coated tablets. Overdose So far, no cases of overdose have been reported. In case of accidental intake in a high dose, induce vomiting, gastric lavage with activated charcoal, symptomatic treatment. Side effects The drug is well tolerated. The following side effects can rarely be observed: from the gastrointestinal tract: nausea, dyspepsia, diarrhea; on the part of the skin and subcutaneous fatty tissue: in some cases, skin allergic reactions are possible – itching, rash; on the part of the organ of hearing and balance: it is rarely possible to observe an increase in existing vestibular disorders. Side effects are transient and disappear after discontinuation of the drug. Storage conditions Store at a temperature not exceeding 25 ° C in a place protected from moisture and light. Keep out of the reach of children! Buy Gepsil-Rn tablets p/o 35mg No. 15×8 Price for Gepsil-Rn tablets p/o 35mg No. 15×8
INN | SILYMARIN |
---|---|
The code | 82 730 |
Barcode | 4 810 243 004 507 |
Dosage | 35mg |
Active substance | Silymarin |
Manufacturer | Rubicon LLC, Belarus |
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