Product DescriptionDiosmin-LF. Forms of release Tablets. MNNdiosmin. DescriptionOblong, pink, biconvex film-coated tablets with a score. The score on the tablets is intended solely to facilitate taking one tablet (by breaking the tablet into two halves), and not to divide the tablet into two doses. Composition Active ingredient: diosmin – 600 mg. Excipients: talc, magnesium stearate, sodium starch glycolate (type A), povidone (K-30), microcrystalline cellulose. Shell composition: Opadry II pink (partially hydrolyzed polyvinyl alcohol, titanium dioxide E171, macrogol/PEG, talc, iron oxide yellow E172, iron oxide red E172, iron oxide/iron oxide black E172). Pharmacotherapeutic group Means that reduce capillary permeability. Bioflavonoids. ATX code C05CA03. Pharmacological action Pharmacodynamics The drug has a phlebotonizing effect (reduces vein extensibility, increases vein tone (dose-dependent effect), reduces venous congestion), improves lymphatic drainage (increases the frequency and tone of contraction of lymphatic capillaries, increases their functional density, reduces lymphatic pressure), improves microcirculation (increases resistance capillaries (dose-dependent effect), reduces their permeability), reduces the adhesion of leukocytes to the venous wall and their migration to paravenous tissues, improves oxygen diffusion and perfusion into skin tissues, and has an anti-inflammatory effect. Enhances the vasoconstrictive action of adrenaline, norepinephrine, blocks the production of free radicals, the synthesis of prostaglandins and thromboxane. Pharmacokinetics Rapidly absorbed from the gastrointestinal tract, found in plasma 2 hours after ingestion. The maximum plasma concentration is reached 5 hours after ingestion. It is evenly distributed and accumulated in all layers of the wall of the vena cava and saphenous veins of the lower extremities, to a lesser extent – in the kidneys, liver and lungs and other tissues. The selective action of diosmin and / or its metabolites in venous vessels reaches a maximum by 9 hours after ingestion and lasts for 96 hours. Excreted by the kidneys 79%, intestines – 11%, with bile – 2.4%. Indications for use As part of complex therapy: • to reduce the symptoms of lymphovenous insufficiency of the lower extremities: a feeling of heaviness and fatigue in the legs, pain; • additional treatment in violation of microcirculation; • symptomatic therapy of acute hemorrhoids. Method of application and dosage Before using the drug, you should consult your doctor. The drug is intended for oral administration. With varicose veins of the lower extremities and chronic lymphovenous insufficiency (edema, pain, convulsions), 1 tablet per day is prescribed in the morning on an empty stomach. With exacerbation of hemorrhoids, the drug is prescribed 2-3 tablets per day with meals. If one or more doses of the drug are missed, it is necessary to continue using the drug as usual and at the usual dose. The duration of admission is determined by the doctor, taking into account the characteristics of the disease, the effect achieved and the tolerability of the drug. Side effects In rare cases, hypersensitivity to the components of the drug, requiring a break in treatment: on the part of the gastrointestinal tract – dyspeptic disorders (heartburn, nausea, abdominal pain); from the side of the central nervous system – headache. If any of the side effects listed in the instructions get worse, or if you notice any other side effects not listed in the instructions, tell your doctor. Contraindications Hypersensitivity to the components of the drug, the period of breastfeeding, children under 18 years of age, pregnancy (I trimester) (experience is limited). Overdose Symptoms of overdose are not described. Precautions: Treatment of an acute attack of hemorrhoids is carried out in combination with other drugs, while Diosmin-LF does not replace the special treatment of other diseases of the anorectal region. In the absence of a rapid clinical effect, it is necessary to conduct an additional examination and adjust the ongoing therapy. If discomfort in the extremities and fragility of the vessels do not decrease after 15 days of using the drug, consult a doctor. If hemorrhoidal disorders persist after several days of using the drug, you should consult your doctor. Compliance with the rules of a healthy lifestyle increases the effectiveness of drug treatment. Avoid exposure to the sun and heat. Do not allow a long standing position, increase in body weight. Walking and wearing compression stockings improve blood circulation. Interaction with other medicinal products No clinically significant effects of interaction with other medicinal products have been described. Use during pregnancy and lactation So far, in clinical practice, there have been no reports of any side effects when using the drug in pregnant women. Application during pregnancy in the II and III trimesters is possible only on prescription in cases where the expected benefit to the mother outweighs the potential risk to the fetus. In experimental studies, no teratogenic effects on the fetus have been identified. During breastfeeding, the drug is not recommended, because. there is no data on the penetration of the drug into breast milk. Influence on the ability to drive vehicles and control mechanisms There is no evidence of a negative effect of the drug on the ability to drive vehicles and other mechanisms. Storage conditions In a place protected from moisture and light at a temperature not exceeding 25 ° C. Keep out of the reach of children. Shelf life 3 years. Do not use after the expiry date stated on the package. Packing: 10 tablets in a blister pack made of PVC film and aluminum foil. Three or six blister packs with instructions for use in a cardboard box. Holiday conditions Without a prescription. Buy Diosmin-LF tablets p/o 600mg No. 10×3 Price for Diosmin-LF tablets p/o 600mg No. 10×3
Diosmin-LF tablets p/o 600mg №10×3
$36.00
SKU: 147276
Category: Treatment and prevention of hemorrhoids and varicose veins
INN | DIOSMIN |
---|---|
The code | 147 276 |
Barcode | 4 812 608 010 239 |
Active substance | Diosmin |
Manufacturer | Lekpharm SOOO, Belarus |
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