Name:
Cerepro.
Description:
Capsules are soft gelatinous, oblong in shape, from red to brown. The main active ingredient is choline alfoscerate. Release formCapsules. Dosage 400mg. Pharmacological action Pharmacodynamics Choline alfoscerate is a transport form of choline and a precursor of phosphatidylcholine, which is potentially able to prevent membrane damage, as one of the pathogenesis factors of psychoorganic involutional syndrome, characterized by a decrease in cholinergic synaptic transmission and damage to the phospholipid composition of neuronal membranes. The chemical structure of choline alfoscerate (containing 40.5% choline) and the physicochemical properties of the molecule associated with it ensure that part of the choline penetrates the blood-brain barrier. The results of preclinical and clinical studies confirm the ability of choline alfoscerate to influence mainly cognitive-mnestic functions, as well as emotional and behavioral activity, impaired in involutional pathology of the brain. Pharmacokinetics Pharmacokinetic characteristics of a radioactively labeled drug when administered were similar in different animal species (rats, dogs, monkeys) and gave the following results: rapid and complete absorption in the gastrointestinal tract, distribution of choline and its metabolites in various organs and tissues, including the brain , renal excretion was about 10% of the administered dose at 96 hours; the content of the drug in the brain tissues is higher compared to tritium-labeled choline. Indications for use Psychoorganic syndrome due to involution and degenerative processes in the brain; the consequences of cerebrovascular insufficiency, such as primary and secondary cognitive impairment in the elderly, characterized by memory impairment, confusion, disorientation, decreased motivation, initiative, and ability to concentrate. Behavioral and affective disorders in old age: emotional lability, increased irritability, decreased interest. Dosage and Administration The recommended dose is 1 capsule 2-3 times a day before meals. If necessary, the dosage can be increased on the recommendation of the attending physician. The duration of the course of treatment is determined by the doctor, taking into account the disease, the tolerance of the drug and the effect achieved. Use during pregnancy and lactation The use of the drug Cerepro during pregnancy and lactation (breastfeeding) is contraindicated. Precautions If there is no improvement, worsening of the condition, or if you have additional questions, you should consult a doctor. The drug contains sorbitol solution, non-crystallizing. In this connection, the drug should not be taken by patients with hereditary fructose intolerance. Due to the content of glycerin, the drug may cause headache, indigestion and diarrhea (diarrhea). Since the drug contains E-218 methyl parahydroxybenzoate and E-216 propyl parahydroxybenzoate, allergic reactions (including delayed ones) are possible. Use in children The drug is not intended for use in children under 18 years of age. There is no experience with the use of Cerepro in children. Interaction with other drugs Drug interaction of the drug Cerepro has not been established. Contraindications: pregnancy; lactation period; children’s age (up to 18 years); hypersensitivity to the components of the drug. Composition One capsule contains: glycerylphosphorylcholine hydrate (choline alfoscerate) – 400.0 mg. Excipients: glycerin, purified water. The composition of the capsule shell: gelatin, glycerin, non-crystallizing sorbitol solution, purified water, methyl parahydroxybenzoate E-218, propyl parahydroxybenzoate E-216, titanium dioxide E-171, iron oxide red E-172. Overdose Symptoms: nausea. When this symptom appears, it is recommended to reduce the dose of the drug. In case of overdose, symptomatic therapy is indicated. The efficacy of dialysis has not been established. Side effect Nausea (due to dopaminergic activation), in this case, the dose of the drug should be reduced. Allergic reactions are possible. Very rarely, abdominal pain and short-term confusion are possible. In case of adverse reactions, including those not listed in this leaflet, you should consult a doctor. Storage conditions Store in a place protected from moisture and light at a temperature not exceeding 25 ° C. Store in a place inaccessible to children. Buy Cerepro capsules 400mg №14х1 Price for Cerepro capsules 400mg №14х1Instruction for use for Cerepro capsules 400mg №14х1
INN | CHOLINA ALPHOSCERATH |
---|---|
The code | 40 854 |
Barcode | 4 810 046 003 363 |
Dosage | 400mg |
Active substance | Choline alfoscerate |
Manufacturer | Veropharm JSC for MIK, Belarus |
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