Ascorbic acid tablets №10

Name:
Ascorbic acid dietary supplement tabl. 2.6 g №10
Description:
Tablets of white or white color with a yellowish tint, with a flat surface, with a notch and a bevel. The main active ingredient is ascorbic acid. Product form Tablets Dosage 2.6 g Pharmacological action Ascorbic acid (vitamin C) has pronounced restorative properties. Belongs to the group of water-soluble vitamins. Participates in redox reactions, regulation of carbohydrate metabolism, affects the metabolism of aromatic amino acids, thyroxine metabolism, biosynthesis of catecholamines, steroid hormones and insulin, is necessary for blood coagulation, collagen and procollagen synthesis, regeneration of connective and bone tissue. Improves capillary permeability. Promotes the absorption of iron in the intestines and takes part in the synthesis of hemoglobin. It increases the nonspecific resistance of the body, has a nonspecific general stimulating effect on the body. Deficiency of vitamin C in food leads to the development of hypo- and avitaminosis C, since this vitamin is not synthesized in the body. Indications for use Prevention and treatment of vitamin C deficiency. Conditions of increased need for ascorbic acid: a period of intensive growth, unbalanced nutrition, increased mental and physical stress, a period of convalescence after serious illness, febrile conditions against the background of acute respiratory diseases, acute respiratory viral infections, long-term current chronic infections. Dosage and administration The drug is taken orally after meals. For the purpose of prevention, adults and children over 14 years of age should take 2-4 tablets (50-100 mg) per day, children aged 6 to 14 years – 1-2 tablets (25-50 mg) per day. Therapeutic doses for adults and children over 14 years of age are 2-4 tablets (50-100 mg) 3-5 times a day, for children from 6 to 10 years old – 4 tablets (100 mg) 2-3 times a day, for children aged 10 to 14 years – 4-6 tablets (100-150 mg) 2-3 times a day. The dosage and course of treatment depend on the nature and characteristics of the course of the disease and are determined by the doctor. If you miss a dose, it is not recommended to take a double dose to make up for the missed one. Use during pregnancy and lactation During pregnancy and lactation, use only if the intended benefit to the mother outweighs the risk to the fetus and child. The daily need for ascorbic acid in the 2-3 trimesters of pregnancy is about 90 mg. It should be borne in mind that the fetus can adapt to high doses of ascorbic acid, which is taken by a pregnant woman, and then the newborn may develop a “withdrawal” syndrome. Theoretically, there is a danger to the child when the mother uses high doses of ascorbic acid (it is recommended not to exceed the daily need for ascorbic acid by the nursing mother). The recommended daily requirement for ascorbic acid during lactation is 120 mg. Precautions Care should be taken when prescribing ascorbic acid to patients with increased blood clotting, hemochromatosis, sideroblastic anemia, sickle cell anemia, thalassemia, hyperoxaluria, nephrolithiasis, polycythemia, leukemia. When taking large doses and long-term use of the drug, kidney function and blood pressure levels, as well as pancreatic function, should be monitored. Use with caution in patients with deficiency of glucose-6-phosphate dehydrogenase (may cause hemolysis of red blood cells). In patients with high iron content in the body, ascorbic acid should be used in minimal doses. The simultaneous use of ascorbic acid with deferoxamine enhances the excretion of iron. In patients with idiopathic hemochromatosis and thalassemia treated with deferoxamine, cases of cardiomyopathy and congestive heart failure have been recorded after taking ascorbic acid. In these situations, ascorbic acid should be administered with caution, monitoring of cardiac function is necessary. The absorption of ascorbic acid can be impaired in intestinal dyskinesias, enteritis and achilia. The use of ascorbic acid in patients with rapidly progressing and intensively metastasizing malignant neoplasms can aggravate the course of the process. Concomitant use of vitamin C with antacids containing aluminum may increase the excretion of aluminum in the urine. The simultaneous use of antacids and ascorbic acid is not recommended in patients with renal insufficiency. Increased consumption of ascorbic acid over a long period can lead to increased renal clearance and deficiency of ascorbic acid upon abrupt withdrawal of the drug. Large doses of ascorbic acid are associated with the formation of calcium oxalate stones in the kidneys. The use of ascorbic acid in therapeutic doses may distort the results of tests to determine glucosuria. Vitamin C may interfere with uric acid measurements using the phosphotungstate or uricase copper and creatinine reduction method in non-deproteinized serum. Ascorbic acid, as a reducing agent, can distort the results of various laboratory tests (blood glucose, bilirubin, transaminase activity, lactate dehydrogenase). The drug is not recommended to be used simultaneously with other drugs containing ascorbic acid. Interaction with other drugs Increases the concentration of benzylpenicillin and tetracyclines in the blood; at a dose of 1 g / day increases the bioavailability of ethinylestradiol. Improves the absorption of iron preparations in the intestines (converts ferric iron to ferrous). May increase iron excretion when used concomitantly with deferoxamine. The combined intake of vitamin C and deferoxamine increases the tissue toxicity of iron, especially in the heart muscle, which can lead to decompensation of the circulatory system. Vitamin C can be taken 2 hours after deferoxamine injection. Acetylsalicylic acid (ASA), oral contraceptives, fresh juices and alkaline drinks reduce the absorption and absorption of ascorbic acid. With simultaneous use with ASA, the excretion of ascorbic acid in the urine increases and the excretion of ASA decreases. ASA reduces the absorption of ascorbic acid by about 30%. Increases the risk of developing crystalluria in the treatment of short-acting salicylates and sulfonamides, slows down the excretion of acids by the kidneys, increases the excretion of drugs that have an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives in the blood. Preparations of the quinoline series (fluoroquinolones, etc.), calcium chloride, salicylates, glucocorticosteroids with prolonged use deplete the reserves of ascorbic acid. With simultaneous use reduces the chronotropic effect of isoprenaline. Increases the overall clearance of ethanol, which, in turn, reduces the concentration of ascorbic acid in the body. Long-term use of high doses by persons treated with disulfiramine inhibits the disulfiram-alcohol reaction. In high doses, it increases the renal excretion of mexiletin. Barbiturates and primidone increase the excretion of ascorbic acid in the urine. Reduces the therapeutic effect of antipsychotics (phenothiazine derivatives), tubular reabsorption of amphetamine and tricyclic antidepressants. Contraindications Hypersensitivity, thrombophlebitis, tendency to thrombosis; with prolonged use in high doses (more than 500 mg) – diabetes mellitus, hyperoxaluria, nephrolithiasis, hemochromatosis, thalassemia, deficiency of glucose-6-phosphate dehydrogenase; children’s age up to 6 years (for this dosage form). Composition Each tablet contains: active substance: ascorbic acid – 25 mg; excipients: powdered sugar, calcium stearate microangiopathy), inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis, damage to the glomerular apparatus of the kidneys. Treatment: drug withdrawal. Symptomatic therapy is shown. Side effects From the side of the central nervous system: with prolonged use of large doses (more than 1,000 mg) – headache, increased excitability of the central nervous system, insomnia. From the urinary system: moderate pollakiuria (when taking a dose of more than 600 mg / day), with prolonged use of large doses – hyperoxaluria, nephrolithiasis (from calcium oxalate), damage to the glomerular apparatus of the kidneys. From the digestive system: when taken orally – irritation of the mucous membrane of the gastrointestinal tract, with prolonged use of large doses – nausea, vomiting, diarrhea, hyperacid gastritis, ulceration of the mucous membrane of the gastrointestinal tract. From the side of the cardiovascular system: with prolonged use of large doses – a decrease in capillary permeability (possible deterioration of tissue trophism, increased blood pressure, hypercoagulability, development of microangiopathies). Allergic reactions: skin rash, skin hyperemia. Laboratory indicators: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia, glucosuria. Others: inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria). With prolonged use, a violation of the exchange of zinc, copper is possible. In case of adverse reactions, including those not listed in this leaflet, you should consult a doctor. Storage conditions In a place protected from moisture and light at a temperature not exceeding 25 ° C. Keep out of the reach of children. Buy Ascorbic acid tablets No. 10 Price for Ascorbic acid tablets No. 10 Instructions for use for Ascorbic acid tablets No. 10