Ascorbic acid dragee 50mg №200

Name:
Ascorbic acid 50mg in polym. No. 200 jars in pack No. 1
Description:
Dragee of greenish-yellow or yellow color, spherical shape, uniform color. Dosage 50 mg Pharmacological action Ascorbic acid is actively involved in many redox reactions, has a non-specific general stimulating effect on the body. Increases the adaptive capacity of the body and its resistance to infections; promotes regeneration processes. Indications for use Prevention and treatment of hypo- and avitaminosis of vitamin C. As an aid: hemorrhagic diathesis, nasal, uterine, pulmonary bleeding; overdose of anticoagulants; diseases of the gastrointestinal tract, accompanied by impaired absorption of vitamin C; slowly healing wounds. Increased physical and mental stress, the period of pregnancy and breastfeeding, the period of recovery after severe long-term illnesses. Dosage and administration The drug is taken orally after meals. For prevention: adults, 0.05-0.1 g (1-2 tablets) per day, children from 5 years old, 0.05 g (1 tablet) per day. For treatment: adults 0.05-0.1 g (1-2 tablets) 3-5 times a day, children from 5 years old 0.05-0.1 g (1-2 tablets) 2-3 times a day day. During pregnancy and breastfeeding, 0.3 g (6 tablets) per day for 10-15 days, then 0.1 g (2 tablets per day) per day. Use during pregnancy and lactation The minimum daily requirement for ascorbic acid in the II-III trimesters of pregnancy is about 60 mg. The minimum daily requirement during breastfeeding is 80 mg. A mother’s diet containing an adequate amount of ascorbic acid is sufficient to prevent vitamin C deficiency in an infant (it is recommended that the nursing mother not exceed the maximum daily requirement for ascorbic acid). Precautions Due to the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor adrenal function and blood pressure. With prolonged use of large doses, inhibition of the function of the insular apparatus of the pancreas is possible, therefore, in the course of treatment, it must be regularly monitored. In patients with high iron content in the body, ascorbic acid should be used in minimal doses. The appointment of ascorbic acid to patients with rapidly proliferating and intensively metastasizing tumors can aggravate the course of the process. Ascorbic acid, as a reducing agent, can distort the results of various laboratory tests (blood glucose, bilirubin, transaminase activity, LDH). Interaction with other drugs Increases the concentration of benzylpenicillin and tetracyclines in the blood; at a dose of 1 g / day increases the bioavailability of ethinylestradiol. Improves absorption in the intestines of iron preparations (converts ferric iron to ferrous); May increase iron excretion when used concomitantly with deferoxamine. Acetylsalicylic acid (ASA), oral contraceptives, fresh juices and alkaline drinks reduce absorption and assimilation. With simultaneous use with ASA, the excretion of ascorbic acid in the urine increases and the excretion of ASA decreases. ASA reduces the absorption of ascorbic acid by about 30%. Increases the risk of developing crystalluria in the treatment of short-acting salicylates and sulfonamides, slows down the excretion of acids by the kidneys, increases the excretion of drugs that have an alkaline reaction (including alkaloids), reduces the concentration of oral contraceptives in the blood. Increases the overall clearance of ethanol, which, in turn, reduces the concentration of ascorbic acid in the body. Preparations of the quinoline series (fluoroquinolones, etc.), calcium chloride, salicylates, glucocorticosteroids with prolonged use deplete the reserves of ascorbic acid. With simultaneous use reduces the chronotropic effect of isoprenaline. With prolonged use or use in high doses, the interaction of disulfiram-ethanol can be disrupted. In high doses, it increases the renal excretion of mexiletin. Barbiturates and primidone increase the excretion of ascorbic acid in the urine. Reduces the therapeutic effect of antipsychotics (phenothiazine derivatives), tubular reabsorption of amphetamine and tricyclic antidepressants. Contraindications Hypersensitivity to the components of the drug, thrombophlebitis, a tendency to thrombosis, diabetes mellitus. With caution: Hyperoxalaturia, renal failure, hemochromatosis, thalassemia, polycythemia, leukemia, sideroblastic anemia, glucose-6-phosphate dehydrogenase deficiency, sickle cell anemia, progressive malignant diseases, pregnancy. Composition Ingredients per tablet: Active ingredients: 0.05 g of ascorbic acid Excipients: sugar, starch syrup, sunflower oil, wax, talc, aromatic essence, quinoline yellow dye E-104. Overdose When taking more than 1 g per day, heartburn, diarrhea, difficulty urinating or staining urine red, hemolysis (in patients with glucose-6-phosphate dehydrogenase deficiency) are possible. If any side effects occur, stop taking the drug and consult a doctor. Side effects From the side of the central nervous system (CNS): headache, fatigue, with prolonged use of large doses – increased excitability of the central nervous system, sleep disturbances. From the digestive system: irritation of the gastrointestinal mucosa, nausea, vomiting, diarrhea, stomach cramps. From the endocrine system: inhibition of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria). From the urinary system: when used in high doses, hyperoxaluria and the formation of urinary stones from calcium oxalate. From the side of the cardiovascular system: thrombosis, when used in high doses, an increase in blood pressure, the development of microangiopathy, myocardial dystrophy. Allergic reactions: skin rash, rarely – anaphylactic shock. Laboratory indicators: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia. Others: hypervitaminosis, sensation of heat, with prolonged use of large doses – retention of sodium (Na +) and fluids, impaired metabolism of zinc (Zn2 +), copper (Cu2 +). Storage conditions In a dry, dark place at a temperature not exceeding 25°C. Buy Ascorbic acid dragee 50mg №200 Price for Ascorbic acid dragee 50mg №200Instruction for use for Ascorbic acid dragee 50mg №200