Almagel A suspension for oral administration in a bottle 170ml №1

Name:
Almagel A susp.d / pr.in. in 170ml vial in set with measuring spoons in pack No. 1 Main active ingredient Algeldrate + magnesium hydroxide + benzocaine
Description:
Suspension of white or almost white color. During storage, a layer of clear liquid may be released on the surface. With vigorous shaking of the contents of the vial, the homogeneity of the suspension is restored. Suspension of 170 ml in bottles of polyethylene terephthalate. One bottle in a carton box with a 5 ml measuring spoon and a leaflet. Pharmacological action Antacids, aluminum compounds. Almagel A is a drug that reduces the increased acidity of gastric juice and relieves pain in certain gastrointestinal diseases. It is a balanced gel of aluminum and magnesium hydroxides, which are insoluble, almost not absorbed in the intestines and enter the body in a minimal amount. The drug contains benzocaine (anesthesin), which is a local anesthetic. Almagel A has a local effect on the gastric mucosa and protects it from the irritating effect of hydrochloric acid and other harmful substances and food, and also reduces the activity of pepsin. The drug reduces the acidity in the esophagus. Benzocaine reduces and relieves pain. It has an anti-inflammatory and cytoprotective effect on the mucous membrane of the esophagus, stomach and duodenum. The auxiliary substance sorbitol exhibits a weak carminative and moderate choleretic effect, as well as a moderate laxative effect. Indications for use Short-term symptomatic treatment of inflammatory and erosive lesions of the mucous membranes of the esophagus, stomach or duodenum, which are accompanied by heartburn, discomfort, pain, nausea, vomiting. Interactions with other drugs Please tell your doctor or pharmacist if you are taking or have recently taken other medicines, even if they have not been prescribed for you. When treated simultaneously with other drugs, they should be taken 1-2 hours before or after taking Almagel A. Almagel A reduces the acidity of gastric juice, and this can affect the effect of a large number of drugs when taken simultaneously. Almagel A reduces the absorption of digoxin, indomethacin, salicylates, chlorpromazine, phenytoin, reserpine, H2-blockers (cimetidine, ranitidine, famotidine), lansoprazole, P-blockers (for example, atenolol, metoprolol, propranolol, chloroquine, cycline, diflunisade, diphosphonates, quinolones (ciprofloxacin, norfloxacin, ofloxacin, enoxacin, grepafloxacin), azithromycin, cefpodoxime, pivampicillin, rifampicin, indirect anticoagulants, barbiturates, fexofenadine, sodium fluoride, dipyridamole, zalcitabine, bile acids (chenodeoxycholic and ursodeoxycholic acids), penicillamine, lankyprosolamine, iron salts, lithium preparations, quinidine, mexiletine, phenothiazine preparations, tetracycline antibiotics, lincosamides, phosphorus preparations, anti-tuberculosis preparations (ethambutol, isoniazid (for oral administration), chloroquine, glucocorticoid preparations (interaction with prednisolone and dexamethasone is known), kyexelate and ket conazol. Almagel A reduces the therapeutic effect of sulfonamides, so it should not be taken during treatment with such drugs. When taken simultaneously with drugs offered in the form of enteric tablets, the reduced acidity of gastric juice can lead to accelerated destruction of their membrane and cause irritation of the stomach and duodenum. Almagel A may affect the results of some laboratory and functional studies and tests: it reduces the level of gastric secretion and thereby changes the results of a functional study to determine its acidity; alters the results of tests using technetium (TC99), such as bone scan and some tests for examining the esophagus, increases serum phosphorus levels, serum and urine pH values. Use of the drug and ingestion of food, drinks and alcohol The drug is recommended to be taken undiluted. During treatment with Almagel A, it is necessary to avoid the use of alcohol and acids (lemon juice, vinegar, etc.), due to the possibility of weakening the local anesthetic effect of benzocaine. Use during pregnancy and lactation Before taking any medicines, consult your doctor or pharmacist. Almagel A is not prescribed during pregnancy and lactation, as it contains benzocaine. Contraindications The drug is not prescribed for children under 18 years of age (risk of developing methemoglobinemia), pregnant and lactating women. Almagel A is contraindicated in: hypersensitivity to any active and / or excipients that make up the drug, hypersensitivity to anesthetics, chronic constipation, chronic diarrhea, severe abdominal pain of unspecified origin, suspected acute appendicitis, Alzheimer’s disease, severe renal failure (risk of hypermagnesemia and aluminum intoxication), hypophosphatemia. Active ingredients: 5 ml (1 scoop) suspension contains: aluminum hydroxide gel, corresponding to 218 mg of aluminum oxide, magnesium hydroxide paste 350 mg, corresponding to 75 mg of magnesium oxide, benzocaine 109 mg. 10 ml (1 package) suspension contains: aluminum hydroxide gel, corresponding to 436 mg of aluminum oxide, magnesium hydroxide paste 700 mg, corresponding to 150 mg of magnesium oxide, benzocaine 218 mg. Excipients: hydrogen peroxide solution (30%), sorbitol, hydroxyethylcellulose, methyl parahydroxybenzoate, propyl parahydroxybenzoate, butyl parahydroxybenzoate, sodium saccharin, propylene glycol, macrogol 4000, lemon oil, ethyl alcohol 96%, purified water. Dosage and Administration Always take Almagel A exactly as directed in this package leaflet. If you are not sure about something, ask your doctor or pharmacist. The usual dose is: Adults: 5-10 ml (1-2 scoops or 1 packet) 3-4 times a day 10-15 minutes before meals. The maximum duration of treatment is 6-7 days, then they switch to treatment with Almagel. It is not recommended to take liquids within 15 minutes after taking it. Before each dose, the suspension must be thoroughly homogenized by shaking the package! If you miss taking the drug If you forget to take Almagel A, take the drug as soon as possible, until the time of the next dose is approaching. If it is time for your next dose, do not take the missed dose. You can not double the dosage of the drug to compensate for the missed! Further, the drug is used according to the recommended dosing regimen. If you have any further questions on the use of this medicine, please ask your doctor or pharmacist. Overdose If you have taken a higher dose than you have been prescribed, seek medical attention immediately! With a single dose in excess of that prescribed by a doctor, there are usually no other signs of an overdose other than constipation, flatulence (increased gas production in the intestines), a metallic taste and loss of sensitivity when swallowing due to the presence of benzocaine in the preparation. With prolonged use of higher doses, swallowing disorders, the formation of kidney stones, the appearance of severe constipation, mild drowsiness, and an increase in the level of magnesium in the blood are possible. There may also be signs of metabolic alkalosis (changes in the acid-base balance in the body): changes in mood or mental activity, numbness or muscle pain, nervousness and fatigue, slow breathing, unpleasant taste sensations. It is necessary to immediately take measures to quickly remove the drug from the body: stimulate vomiting, wash the stomach, take activated charcoal. If symptoms of an overdose appear, consult a doctor immediately! Side effects Like all medicines, Almagel A can cause side effects, although not everybody gets them. The evaluation of undesirable adverse reactions is based on the following data on the frequency of occurrence: very often (> 1/10), often (> 1/100 to <1/10), infrequently (> 1/1000 to <1/100), rarely (> 1/10000 to <1/1000), very rare (<1/10000), not known (cannot be estimated from the available data). From the gastrointestinal tract: Unknown: possible manifestations of constipation, which disappear with a decrease in dose, diarrhea, discoloration of feces; nausea, vomiting, stomach cramps; From the immune system: Not known: allergic reactions of local and general type, including itching, urticaria, angioedema and anaphylactic reactions. Laboratory indicators: Unknown: most often in patients with renal insufficiency and in the case of prolonged use or taking high doses of the drug due to hypermagnesemia, hyperaluminemia, aluminum and magnesium intoxication develops; hypophosphatemia (manifestations of which may be loss of appetite, muscle weakness, weight loss); possible hypocalcemia, hypercalciuria; From the side of the central nervous system: It is not known: with prolonged use of the drug in patients with renal insufficiency and patients on dialysis, manifestations of encephalopathy, neurotoxicity (changes in mood and mental activity), dementia, deterioration in Alzheimer's disease are possible. If any side reaction becomes serious, or if you experience any side effects not described in this leaflet, please contact your doctor or pharmacist. Storage conditions In a place protected from light at a temperature not exceeding 25 ° C. Do not freeze! Keep out of the reach of children! 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