Description: Round, flat white tablets, engraved on one side with “ALKA SELTZER” in a convex circle protruding around the perimeter. The reverse side has a chamfer. The main active ingredient Acetylsalicylic acid + citric acid + sodium bicarbonate Release form Effervescent tablets Special instructions and precautions The drug should be taken with extreme caution in the following cases: hypersensitivity to other analgesics / anti-inflammatory / antirheumatic drugs or other allergenic substances; ASA can cause bronchospasm, an attack of bronchial asthma, especially in the presence of allergies (for example, with a skin reaction, itching, urticaria), a history of bronchial asthma, hay runny nose, nasal polyposis, chronic bronchopulmonary diseases; simultaneous therapy with anticoagulants; history of stomach ulcer or gastrointestinal bleeding; limited liver function; for patients with limited renal function or with reduced cardiovascular circulation; functional disorders of the kidneys or acute renal failure; if surgical interventions are necessary (also with minor interventions, such as tooth extraction), may increase the tendency to bleed; for patients with increased deficiency of glucose-6-phosphate dehydrogenase: ASA can lead to hemolysis or hemolytic anemia. The risk of hemolysis is increased with high dosage, elevated temperature, or acute infections. One tablet of Alka-Seltzer contains 477 mg of sodium, which should be taken into account when dieting with a controlled intake of sodium. The content of sodium benzoate in suitable patients with a predisposition can lead to allergic reactions in the form of irritation on the skin and mucous membranes. With prolonged use of painkillers, headaches can occur, which lead to repeated administration of the drug, which can again cause prolonged headaches. Taking painkillers can lead to long-term kidney problems with a risk of kidney failure (analgesic nephropathy). This risk is especially increased with the combined use of various painkillers. ASA in small doses reduces the excretion of uric acid. Exacerbation of gout is possible in patients with a tendency to low diuresis. Adolescents over 15 years of age should take ASA only under medical supervision and only when other drugs have failed. In children and adolescents under 15 years of age, when using ASA for viral diseases such as influenza type A, influenza type B, chicken pox, there is a risk of developing Reye’s syndrome. Symptoms of Reye’s syndrome are prolonged vomiting, acute encephalopathy, liver enlargement. Pharmacotherapeutic properties Combined drug, the action of which is due to its constituent active ingredients. Acetylsalicylic acid (ASA) has an analgesic, antipyretic, anti-inflammatory effect, which is due to the inhibition of cyclooxygenase enzymes involved in the synthesis of prostaglandins; inhibits platelet aggregation by blocking the synthesis of thromboxane Ag. In the treatment of vascular diseases, the daily dose of acetylsalicylic acid ranges from 75 to 300 mg. Sodium carbonate neutralizes free hydrochloric acid in the stomach, which reduces the irritant effect of the drug. Citric acid promotes rapid absorption of the drug. Indications for use For the symptomatic relief of headache, toothache, sore throat, back and muscle, joint, menstrual pain. Increased body temperature in colds and other infectious and inflammatory diseases in adults and children over 15 years of age. Dosage and administration Dissolve the tablet/tablets in a glass of water and drink. Adults and adolescents over 15 years of age: a single dose is 1-2 effervescent tablets, the maximum daily dose should not exceed 8 tablets. If necessary, a single dose can be taken at intervals of 4-8 hours up to 3 times a day. For the elderly: the usual dose is 1 tablet, in case of more severe pain or fever, take 2 tablets. In both cases, if necessary, the reception can be repeated, but not earlier than after 4 hours. The maximum daily dose is 4 tablets. The duration of treatment (without consulting a doctor) should not exceed 5 days when prescribed as an anesthetic and 3 days as an antipyretic. Use during pregnancy and lactation Inhibitors of prostaglandin synthesis may adversely affect the course of pregnancy and / or the development of the embryo / fetus. In early pregnancy, the risk of miscarriage and malformations increases with increasing dosage and duration of the drug. During the 3rd trimester of pregnancy, the following risks are possible: kidney dysfunction, which can subsequently lead to kidney failure and oligohydramnios; the fetus has cardiopulmonary toxicity. In the mother and in the child in the last months of pregnancy – an increase in blood clotting is possible; antiaggregatory effect; weakening of labor pains. Salicylates and their metabolites pass into breast milk in small amounts, which causes a risk of bleeding in the child due to impaired platelet function. Since to date there have been no cases of adverse effects on the infant after an accidental (single) administration of the drug, there is no need to interrupt breastfeeding. However, if taken regularly or if large doses are taken, breastfeeding should be discontinued. Medications that inhibit cyclooxygenase / prostaglandin synthesis lead to impaired female fertility, as they affect the ovulation process. This process is reversible after cessation of treatment. Interaction with other drugs Increases the hepatotoxicity of methotrexate due to a decrease in the renal clearance of methotrexate by anti-inflammatory agents and its displacement from its association with plasma proteins. Enhances the effects of hypoglycemic drugs, heparin, sulfonamides, triiodothyronine, reserpine. Anticoagulants, thrombolytics, and inhibitors of platelet aggregation increase the risk of bleeding. Selective serotonin reuptake inhibitors: increase the risk of ulcerative lesions and gastrointestinal disease due to a synergistic effect. The concentration of digoxin, barbiturates and lithium preparations in the blood plasma increases due to a decrease in renal excretion. Antidiabetic drugs (eg, insulin, sulfonylurea) increase the hypoglycemic effect. Diuretics in combination with a high dose of ASA and angiotensin-converting enzyme inhibitors reduce glomerular filtration. Systemic glucocorticosteroids reduce the level of salicylates in the blood plasma during treatment, and after the end of use, they increase the risk of overdose of salicylates: an increased risk of developing gastrointestinal side effects. The toxicity of valproic acid increases as a result of its displacement from its association with blood plasma proteins. Alcohol increases the damaging effect on the gastrointestinal mucosa, increases the risk of gastrointestinal bleeding. Reduces the effects of uricosuric drugs (eg, benzbromarone, probenecid), antihypertensives and diuretics. Antacids containing magnesium and / or aluminum hydroxide slow down and impair the absorption of ASA. Contraindications Hypersensitivity to ASA and other NSAIDs or other components of the drug; active peptic ulcer; hemorrhagic diathesis; combined use of methotrexate at a dose of 15 mg per week or more; asthma caused by taking salicylates or other NSAIDs; severe chronic renal and / or liver failure; severe chronic heart failure; pregnancy (III trimester); children and adolescents under 15 years of age. Active ingredients: acetylsalicylic acid 324 mg, anhydrous citric acid 965 mg, sodium bicarbonate 1625 mg. Excipients: povidone 25, siloxane/silicate, doss sodium benzoate, sodium saccharin, lemon and lime flavors. Overdose Intoxication in the elderly should be feared (therapeutic overdose or extensive intoxication can be fatal). Symptoms of an overdose of moderate severity: nausea, vomiting, tinnitus, hearing loss, headache, dizziness and confusion. These symptoms disappear with a decrease in the dose of the drug. Severe overdose: fever, hyperventilation, ketosis, respiratory alkalosis, metabolic acidosis, coma, cardiogenic shock, respiratory failure, severe hypoglycemia. Treatment: hospitalization, lavage, activated charcoal, acid-base balance monitoring, alkaline diuresis, hemodialysis, fluid replacement, symptomatic therapy. Side effectDiseases of the blood and lymphatic system: rarely – serious bleeding, for example, cerebral hemorrhage, especially in patients with undiagnosed high blood pressure and / or with simultaneous therapy with anticoagulants, which in some cases can be fatal. Bleeding from the nose, bleeding gums, skin bleeding or bleeding from the urogenital tract with possibly prolonged blood clotting. The effect stops 4-8 days after stopping the drug. Hemolysis and hemolytic anemia have been reported in patients with severe glucose-6-phosphate dehydrogenase deficiency. Gastrointestinal diseases: rarely – heartburn, nausea, vomiting, abdominal pain, stomach ulcers, gastrointestinal bleeding. CNS diseases: headaches, dizziness, hearing impairment, tinnitus (tinnitus) and confusion. Skin diseases: infrequently – allergic reactions. Diseases of the immune system: rarely – allergic reactions of the respiratory tract, gastrointestinal tract and cardiovascular system, especially in patients with asthma. Symptoms can be: low blood pressure, cases of suffocation, rhinitis, nasal congestion, anaphylactic shock or Quincke’s edema. Diseases of the liver and gallbladder: very rarely – an increase in liver parameters. Diseases of the kidneys and urinary tract: functional disorders of the kidneys and acute renal failure. If such symptoms appear, it is recommended to stop taking the drug and consult a doctor immediately. Storage conditions At a temperature not exceeding 25 ° C, out of the reach of children. Buy Alka-Seltzer effervescent tablets 324mg No. 2×5
Alka-Seltzer effervescent tablets 324mg №2×5
$32.00
SKU: 49117
Category: Medicines for pain and inflammation
INN | ACETYLSALICYLIC ACID |
---|---|
The code | 49 117 |
Barcode | 4 250 369 504 138 |
Active substance | Acetylsalicylic acid, citric acid, sodium bicarbonate |
Manufacturer | Bayer Bitterfeld, Germany |
Importer | Foreign trade unitary enterprise "BELTRANSFER-MED", 220073 Minsk, Olshevsky str., 20/11-24, 8th floor, room 20 |
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