Alflutop solution for intramuscular and intramuscular injection 0.1ml/1ml in ampoules 2ml №5×1

NameAlflutop solution for intramuscular and intramuscular injection 0.1ml/1ml in 2ml amp. The main active ingredient is a bioactive concentrate from small marine fish. Release form The solution for injection is clear, colorless or slightly brownish-yellow, or slightly yellow. 1 ml bioactive concentrate from small marine fish (North Sea sprat (Sprattus sprattus sprattus), herring family (Clupeidae); Black Sea whiting (Odontogadus merlangus euxinus), cod family (Gadidae); Black Sea shad (Alosa tanaica nordmanni), herring family (Clupeidae) ; Black Sea anchovy (Engraulis encrasicholus ponticus), anchovy family (Engraulidae)), obtained by extraction followed by deproteinization and delipidization 0.1 ml Excipients: phenol – no more than 0.005 g, water for injection – up to 1 ml. 2 ml – dark glass ampoules (5) – cell polymer packaging (1) – cardboard packs. 2 ml – syringes pre-filled with a capacity of 2.25 ml made of colorless glass (1) – cellular polymer packaging (5) with disposable needles (5 pcs.) – packs of cardboard. Special instructionsIn case of individual intolerance to seafood (sea fish), the risk of developing allergic reactions increases. Pharmacological action Alflutop is a chondroprotector, the active component of which is a bioactive concentrate from small marine fish. The concentrate contains mucopolysaccharides (chondroitin sulfate), amino acids, peptides, sodium, potassium, calcium, magnesium, iron, copper and zinc ions. Alflutop prevents the destruction of macromolecular structures of normal tissues, stimulates recovery processes in the interstitial tissue and articular cartilage tissue, which explains its analgesic effect. The anti-inflammatory effect and tissue regeneration are based on inhibition of hyaluronidase activity and normalization of hyaluronic acid biosynthesis. Both of these effects are synergistic and cause the activation of regenerative processes in tissues, in particular, the restoration of the cartilage structure. Pharmacokinetics The action of an extract of marine organisms is the cumulative action of its active components, therefore, the study of pharmacokinetic characteristics is not possible. Indications for use – primary and secondary osteoarthritis of various localization (coxarthrosis, gonarthrosis, arthrosis of small joints); – spondylosis; – osteochondrosis. Dosage and administration In polyosteoarthrosis and osteochondrosis, the drug is administered deeply intramuscularly, 1 ml per day. The course of treatment is 20 injections (1 injection per day for 20 days). With a predominant lesion of large joints, the drug is administered intra-articularly, 1-2 ml into each joint with an interval of 3-4 days. The course of treatment is 5-6 injections in each joint. Perhaps a combination of / m and intra-articular injection. It is advisable to repeat the course of treatment 6 months after consulting a doctor. Use during pregnancy and lactation The drug is contraindicated for use during pregnancy and lactation. Precautions Use in children Contraindicated in children. It is not recommended to prescribe the drug in adolescence due to the lack of scientific clinical data in this category of patients. Interaction with other drugs To date, drug interactions with Alflutop have not been identified. Contraindications – hypersensitivity to the components of the drug; – pregnancy; – lactation period (breastfeeding); – childhood; It is not recommended to prescribe the drug in adolescence due to the lack of scientific clinical data in this category of patients. CompositionBioactive concentrate from small marine fish (North Sea sprat (Sprattus sprattus sprattus), herring family (Clupeidae); Black Sea whiting (Odontogadus merlangus euxinus), cod family (Gadidae); Black Sea shad (Alosa tanaica nordmanni), herring family (Clupeidae); anchovy Black Sea (Engraulis encrasicholus ponticus), anchovy family (Engraulidae)), obtained by extraction followed by deproteinization and delipidization 0.1 ml Excipients: phenol – no more than 0.005 g, water for injection – up to 1 ml. Overdosage In predisposed patients, allergic reactions are possible, sometimes severe. Side effects Rarely: itchy dermatitis, redness of the skin, burning sensation at the injection site, short-term myalgia. Very rare: anaphylactic reactions. In some cases: transient increase in pain syndrome (with intra-articular injection). Storage conditions The drug should be stored out of the reach of children, protected from light at a temperature of 15° to 25°C. Leave conditions By prescription. Buy Alflutop solution for intramuscular and intramuscular injection 0.1ml/1ml in ampoules 2ml No. 5×1 Alflutop solution for intramuscular and intramuscular injection 0.1ml/1ml in ampoules 2ml №5×1