Magnerot tab.500mg in a blister pack No. 10×2

Name Magnerot tabl. Release form Release form: tablets, 500 mg, 10 tablets in a blister made of PVC / PVDC film and aluminum foil. 2 or 5 blisters of 10 tablets together with instructions for use in a cardboard box. Special instructions READ THE FULL INSTRUCTIONS BEFORE USE! Pharmacological action Magnesium preparation. It is the most important macronutrient, magnesium carries out more than 300 enzymatic reactions, regulation of cell permeability and neuromuscular excitability. Necessary for many energy processes, involved in the metabolism of proteins, fats, carbohydrates and nucleic acids. Magnesium has a curar-like effect on the endings of cholinergic neurons, with a decrease in the release of acetylcholine; magnesium and calcium interact in the body partially synergistically; however, with competitive inhibition of calcium, magnesium can also affect its binding sites as a “physiological calcium antagonist” Absorbed approximately 35-40% of the dose taken. Hypomagnesemia stimulates the absorption of magnesium ions. The presence of salts of orotic acid improves the absorption of magnesium. Magnesium is excreted by the kidneys, excretion decreases with magnesium deficiency and increases with its excess. Pharmacokinetics Approximately 35-40% of the dose taken is absorbed. Hypomagnesemia stimulates the absorption of magnesium ions. The presence of orotic acid salts contributes to the improvement of magnesium absorption. Magnesium is excreted by the kidneys, excretion decreases with magnesium deficiency and increases with its excess. Indications for use Established magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as irritability, minor sleep disturbances, gastrointestinal spasms, fatigue, muscle pain and spasms, tingling sensation in the muscles. Dosage and administration Tablets are taken orally before meals with a small amount of water. 2 tablets 3 times a day for 7 days, then 1 tablet 2-3 times a day daily. The duration of the course of treatment is 4 weeks. Treatment should be stopped immediately after the normalization of the concentration of magnesium in the blood. Use during pregnancy and lactation Use during pregnancy and breastfeeding: May be used during pregnancy on the advice of a physician. Avoid taking the drug during breastfeeding. Interaction with other drugs While taking magnesium-containing drugs with iron preparations, sodium fluoride and tetracyclines, the absorption of the latter may decrease. Therefore, drugs should be taken at intervals of 2-3 hours. Oral contraceptives, diuretics, muscle relaxants, corticosteroids, insulin reduce the effect of the drug. ContraindicationsContraindications: Hypersensitivity to the components of the drug, urolithiasis, impaired renal function, predisposition to the formation of calcium-magnesium-ammonium-phosphate stones, myasthenia gravis, atrioventricular blockade, liver cirrhosis with ascites, children under 18 years of age, lactose intolerance, lactase deficiency or glucose-galactose malabsorption (due to the presence of lactose in the composition). Composition Active ingredient: magnesium orotate dihydrate – 500 mg Overdose With normal kidney function, magnesium intake does not cause toxic reactions. Magnesium poisoning can develop with kidney failure. See complete prescribing information. Side effect Disturbances from the gastrointestinal tract: unstable stools and diarrhea, which disappear on their own with a decrease in the dose of the drug. From the immune system: allergic reactions. Storage conditions The drug should be stored at a temperature not exceeding 25 ° C, out of the reach of children. Shelf life – 5 years. Buy Magnerot tablets 500mg in a blister pack No. 10×2