Acezone 200mg Powder for Oral Solution: Effective Relief from Respiratory Congestion
Description:
Acezone 200mg powder for oral solution is a mucolytic medication used to thin and loosen thick mucus in the respiratory system, making it easier to cough up. Each 3g sachet contains 200mg of acetylcysteine, the active ingredient.
Indications:
Acezone is indicated for the treatment of respiratory conditions characterized by thick, difficult-to-expectorate mucus, including:
- Acute and chronic bronchitis
- Laryngitis
- Sinusitis
- Tracheitis
- Influenza
- Bronchial asthma
- Cystic fibrosis (as an adjunct therapy)
Dosage and Administration:
Acezone is taken orally. The contents of each sachet are dissolved in a glass of cold or warm water. The solution should not be mixed with other medications.
Adults and children over 12 years old:
- Standard dose: 200mg three times daily or 600mg once daily.
- Long-term treatment: 400-600mg per day, in one or more doses, for a maximum of 3 to 6 months.
Children 2 to 12 years old:
- Standard dose: 100mg three times daily or 200mg twice daily.
Cystic fibrosis (adults and children over 6 years old):
200mg three times daily or 600mg once daily.
Duration of treatment:
The duration of the course should be determined by your doctor. For acute illnesses, it typically lasts 5 to 10 days.
Precautions:
- Acezone should be used with caution in patients with a history of gastric ulcers, particularly when taken concurrently with other medications that irritate the stomach lining.
- While rare, severe skin reactions have been reported with acetylcysteine. If you experience any skin changes, discontinue use and consult your doctor.
- Acezone should be used cautiously in patients with bronchial asthma due to the potential risk of bronchospasm.
- It may cause reflex bronchospasm when preparing the solution due to the powder becoming airborne.
- Patients with liver or kidney disease should use Acezone with caution to avoid the buildup of nitrogenous substances in the body.
- Acezone can inhibit diamine oxidase (DAO), which may trigger intolerance symptoms in patients with histamine intolerance.
- Do not combine Acezone with antitussive medications as this can lead to mucus buildup and the risk of bronchospasm.
- Acezone contains sucrose and should not be used in patients with fructose intolerance, sucrase-isomaltase deficiency, or glucose-galactose malabsorption.
- Acezone contains ascorbic acid (vitamin C), which should be considered in patients taking other vitamin C sources.
Interactions:
- Simultaneous use with activated charcoal may decrease the effectiveness of Acezone.
- A 2-hour interval should be maintained between taking antibiotics and Acezone, except for loracarbef.
- Combining Acezone with nitroglycerin may increase the vasodilating and antiplatelet effects of the latter.
- Concomitant use with antitussives should be avoided (see Precautions).
- Acezone may interfere with colorimetric tests for salicylates and urinary ketones.
Contraindications:
- Hypersensitivity to acetylcysteine or any of the excipients.
- Children under 2 years of age.
- Active peptic ulcer.
- Fructose intolerance (due to the presence of sucrose).
- Hyperoxaluria.
Storage:
Store in a dry, light-protected place at a temperature not exceeding 25°C. Keep out of reach of children.
Presentation:
Acezone 200mg is available in packs of 20 sachets, each containing 3g of powder for oral solution.
Consult your doctor or pharmacist for more information about Acezone and its use.
Please note: This information is not a substitute for professional medical advice. Always consult with your doctor or pharmacist before starting any new medication.