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Metformin Pharmland 500mg Tablets: Effective Diabetes Management
Manage your type 2 diabetes effectively with Metformin Pharmland 500mg tablets. This medication helps control blood sugar levels without causing hypoglycemia. Metformin Pharmland is available in convenient 500mg tablets, packaged in packs of 10×3 for a total of 30 tablets.
How Metformin Pharmland Works:
- Improves Insulin Sensitivity: Increases the effectiveness of your own insulin, helping your body use glucose more efficiently.
- Reduces Liver Glucose Production: Inhibits the liver’s production of glucose, lowering blood sugar levels.
- Slows Glucose Absorption: Delays the absorption of glucose from your intestines, further controlling blood sugar spikes.
- Promotes Glycogen Synthesis: Encourages your body to store glucose as glycogen, helping to regulate blood sugar levels.
- Beneficial Lipid Profile: Metformin Pharmland can also help reduce total cholesterol, LDL (bad) cholesterol, and triglycerides, improving overall cardiovascular health.
Key Features:
- Effective Blood Sugar Control: Helps manage type 2 diabetes without causing hypoglycemia.
- Convenient Dosage: Available in 500mg tablets for easy administration.
- Safe and Well-Tolerated: A widely-used and well-tolerated medication for diabetes management.
Important Note:
Always consult with your doctor before taking Metformin Pharmland or any other medication. This information should not be used as a substitute for professional medical advice. Metformin Pharmland is not suitable for everyone. Please discuss your individual needs and potential side effects with your doctor.
Order your Metformin Pharmland 500mg tablets today and start managing your diabetes effectively!
Link to purchase Metformin Pharmland
Keywords: Metformin Pharmland, 500mg tablets, type 2 diabetes, diabetes management, blood sugar control, insulin sensitivity, glucose production, glucose absorption, glycogen synthesis, lipid profile, cholesterol, LDL, triglycerides, cardiovascular health, safe medication, convenient dosage.
| INN | METFORMIN |
|---|---|
| The code | 77 299 |
| Barcode | 4 810 368 008 985 |
| Dosage | 500mg |
| Active substance | Metformin |
| Manufacturer | Pharmland SP LLC, Belarus |
| Indications Applications | Suction. After oral administration, metformin is absorbed from the gastrointestinal tract quite completely. Absolute bioavailability is 50-60%. The maximum concentration (Cmax approximately equal to 2 μg / ml or 15 μmol) in blood plasma is reached after 2.5 hours. With simultaneous intake of food, the absorption of metformin is reduced and delayed. The clinical significance of this phenomenon is not known. Distribution. Metformin is rapidly distributed in tissues, practically does not bind to plasma proteins. The average volume of distribution () ranges from 63-276 liters. Metabolism. It is metabolized to a very low degree. Metformin is excreted unchanged in the urine. Withdrawal. Metformin clearance in healthy individuals is 400 ml / min (4 times greater than creatinine clearance), which indicates the presence of active tubular secretion. The half-life is approximately 6.5 hours. With renal failure, it increases, there is a risk of cumulation of the drug. |
| Contraindications | Hypersensitivity to metformin or to any excipient of the drug; – Diabetic ketoacidosis, diabetic precoma, coma; – Impaired kidney function (creatinine clearance less than 60 ml/min); – Acute conditions that occur with a risk of developing impaired renal function: dehydration (with diarrhea, vomiting), severe infectious diseases, shock; – Clinically pronounced manifestations of acute and chronic diseases that can lead to the development of tissue hypoxia (heart or respiratory failure, acute myocardial infarction, etc.); – Major surgery and trauma when insulin therapy is indicated (see Precautions section); – Liver failure, impaired liver function; – Acute alcohol intoxication, chronic alcoholism; – Pregnancy; – Lactic acidosis (including history); – Use within 48 hours before and after radioisotope or X-ray studies with the introduction of an iodine-containing contrast agent (see the section "Interaction with other drugs"; – Compliance with a hypocaloric diet (less than 100 kcal / day). Use the drug with caution in older patients 60 years of age, performing heavy physical work (which is associated with an increased risk of developing lactic acidosis in them); during breastfeeding. |
| Side effects | These adverse reactions occurred with the following frequency: – Very often (≥1/10); – Often (≥1/100, <1/10); – Not often (≥1/1000, <1/100); – Rarely (≥1/10, 000, <1/1000); – Very rare (<1/10000), including isolated reports. From the gastrointestinal tract: very often: nausea, vomiting, diarrhea, abdominal pain and lack of appetite. Most often they occur at the beginning of treatment and in most cases resolve spontaneously. To prevent the onset of symptoms, the recommended daily dose should be divided into 2 or 3 doses during or after meals. Slow dose escalation may improve gastrointestinal tolerance. From the side of metabolism and nutrition: very rarely: lactic acidosis (see "Special Instructions"). With long-term use of metformin, there may be a decrease in the absorption of vitamin B12, and if megaloblastic anemia is detected in a patient, the possibility of such an etiology must be considered. From the nervous system: often: taste disturbance. From the side of the liver and biliary tract: very rarely: impaired liver function and hepatitis; after the abolition of metformin, these adverse events completely disappear. On the part of the skin and subcutaneous tissue: very rarely: skin reactions such as erythema, itching, rash. Published data, post-marketing data, as well as controlled clinical studies in a limited pediatric population in the 10-16 age group show that side effects in children are similar in nature and severity to those in adult patients. |
| Use during pregnancy and lactation | Forbidden to use |
| Application Gender | Any |
| Release Form | tablets |
| Composition Means | Active ingredient: metformin hydrochloride – 1000 mg; auxiliary ingredients: calcium hydrogen phosphate dihydrate, corn starch, lactose monohydrate, povidone K-30, gelatin, talc, magnesium stearate, sodium croscarmellose; shell: titanium dioxide (E 171), hydroxypropyl methylcellulose, ethyl cellulose, propylene glycol, polyethylene glycol. |
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